Natural killer cell subpopulations in the peripheral blood of single ventricle/hypoplastic left heart syndrome patients via single-cell RNA sequencing

Natural killer cell subpopulations in the peripheral blood of single ventricle/hypoplastic left heart syndrome patients via single-cell RNA sequencing

Natural Killer (NK) cells are integral components of the innate immune system, recognizing and eliminating virus-infected cells. They may play a crucial role in the immune response and contribute to the complications associated with Single Ventricle/Hypoplastic Left Heart Syndrome (SV/HLHS). Utilizi...

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Bibliographic Details
Main Authors: Hui-Qi Qu, Kushagra Goel, Kayleigh Ostberg, Diana J. Slater, Fengxiang Wang, James Snyder, Cuiping Hou, Garnet Eister, John J. Connolly, Michael March, Joseph T. Glessner, Charlly Kao, Hakon Hakonarson
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Experimental Biology and Medicine
Subjects:
NK cells
peripheral blood mononuclear cells
single-cell RNA sequencing
single ventricle/hypoplastic left heart syndrome
transcriptome
Online Access:https://www.ebm-journal.org/articles/10.3389/ebm.2025.10524/full
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