Human umbilical vein endothelial cell miRNA secretome highlights endothelial origin of serum miRNAs

Abstract MicroRNAs are key contributors to blood-based biomarker research, however their potential is hindered by the “noise” of their abundance even in healthy blood. Using HUVEC cultures and their conditioned media as a model for endothelium and blood, we were able to detect 574 different microRNA...

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Bibliographic Details
Main Authors: Nora J. Doleschall, Zoltán F. Doleschall, Flóra Demeter, Márta L. Debreczeni, Erika Kajdácsi, László Cervenak, Katalin Keltai
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-10044-8
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