Feasibility and Acceptability of Using an Evidence-Based Tai Chi Intervention for Managing the Fatigue–Sleep Disturbance–Depression Symptom Cluster in Breast Cancer Patients

<b>Objective:</b> To explore the feasibility and acceptability of using an evidence-based Tai Chi intervention to manage the fatigue–sleep disturbance–depression symptom cluster (FSDSC) in female breast cancer patients. <b>Methods:</b> This study reported the feasibility outc...

Full description

Saved in:
Bibliographic Details
Main Authors: Li-Qun Yao, Tao Wang, Xian-Liang Liu, Jing-Yu (Benjamin) Tan
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Nursing Reports
Subjects:
Online Access:https://www.mdpi.com/2039-4403/15/5/167
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850256256391970816
author Li-Qun Yao
Tao Wang
Xian-Liang Liu
Jing-Yu (Benjamin) Tan
author_facet Li-Qun Yao
Tao Wang
Xian-Liang Liu
Jing-Yu (Benjamin) Tan
author_sort Li-Qun Yao
collection DOAJ
description <b>Objective:</b> To explore the feasibility and acceptability of using an evidence-based Tai Chi intervention to manage the fatigue–sleep disturbance–depression symptom cluster (FSDSC) in female breast cancer patients. <b>Methods:</b> This study reported the feasibility outcomes of a pilot randomized controlled trial (RCT), along with a nested qualitative process evaluation. Seventy-two female breast cancer patients experiencing the FSDSC were randomized into either a Tai Chi group or a control group. The Tai Chi group received an eight-week Tai Chi intervention consisting of two one-hour sessions per week, along with routine care, while the control group received routine care only. The feasibility and acceptability of the study procedure and Tai Chi intervention protocol were assessed by measuring recruitment, referral, retention and drop-out rates, questionnaire completion rates (including the Brief Fatigue Inventory [BFI], Pittsburgh Sleep Quality Index [PSQI], Hospital Anxiety and Depression Scale-Depression [HADS-D], and Functional Assessment of Cancer Therapy-Breast [FACT-B]), intervention adherence, and safety outcomes. The nested qualitative process evaluation consisted of semi-structured interviews conducted among 22 participants to further explore their experiences of participating in this study and practicing Tai Chi. Descriptive data analysis was employed to present the feasibility and acceptability outcomes. Content analysis was employed to analyze the data from the qualitative process evaluation. <b>Results:</b> A total of 72 breast cancer patients were successfully recruited over six months, with a recruitment rate of 79.1%, retention rate of 95.8%, and dropout rate of 4.2%. No missing data was found in the BFI, PSQI, or HADS-D. However, a notable number of missing values were found in the FACT-B, particularly for items related to sexual satisfaction. The Tai Chi intervention demonstrated a high level of feasibility, with an average adherence rate of 86.8%. Only eight participants reported minor discomforts, such as minor musculoskeletal discomfort and dizziness, but they were transient and manageable after stopping Tai Chi practice. Semi-structured interviews with 22 participants highlighted that Tai Chi was experienced to be generally convenient, energy-saving, and low intensity for FSDSC management. Participants also felt that the study questionnaires were comprehensible and straightforward. Many interviewees from the Tai Chi group reported perceiving favorable effects on FSDSC management, as well as overall functional health and well-being. <b>Conclusions:</b> The evidence-based Tai Chi intervention proved feasible, safe, and convenient as a non-pharmacological intervention for managing FSDSC in breast cancer patients. Future large-scale studies are needed to evaluate Tai Chi’s definite effects on improving FSDSC among breast cancer patients.
format Article
id doaj-art-229ddff4b226427a847d2d39096d8d39
institution OA Journals
issn 2039-439X
2039-4403
language English
publishDate 2025-05-01
publisher MDPI AG
record_format Article
series Nursing Reports
spelling doaj-art-229ddff4b226427a847d2d39096d8d392025-08-20T01:56:41ZengMDPI AGNursing Reports2039-439X2039-44032025-05-0115516710.3390/nursrep15050167Feasibility and Acceptability of Using an Evidence-Based Tai Chi Intervention for Managing the Fatigue–Sleep Disturbance–Depression Symptom Cluster in Breast Cancer PatientsLi-Qun Yao0Tao Wang1Xian-Liang Liu2Jing-Yu (Benjamin) Tan3College of Nursing, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, ChinaFaculty of Health, Charles Darwin University, Brisbane Centre, Brisbane, QLD 4000, AustraliaFaculty of Health, Charles Darwin University, Brisbane Centre, Brisbane, QLD 4000, AustraliaFaculty of Health, Charles Darwin University, Brisbane Centre, Brisbane, QLD 4000, Australia<b>Objective:</b> To explore the feasibility and acceptability of using an evidence-based Tai Chi intervention to manage the fatigue–sleep disturbance–depression symptom cluster (FSDSC) in female breast cancer patients. <b>Methods:</b> This study reported the feasibility outcomes of a pilot randomized controlled trial (RCT), along with a nested qualitative process evaluation. Seventy-two female breast cancer patients experiencing the FSDSC were randomized into either a Tai Chi group or a control group. The Tai Chi group received an eight-week Tai Chi intervention consisting of two one-hour sessions per week, along with routine care, while the control group received routine care only. The feasibility and acceptability of the study procedure and Tai Chi intervention protocol were assessed by measuring recruitment, referral, retention and drop-out rates, questionnaire completion rates (including the Brief Fatigue Inventory [BFI], Pittsburgh Sleep Quality Index [PSQI], Hospital Anxiety and Depression Scale-Depression [HADS-D], and Functional Assessment of Cancer Therapy-Breast [FACT-B]), intervention adherence, and safety outcomes. The nested qualitative process evaluation consisted of semi-structured interviews conducted among 22 participants to further explore their experiences of participating in this study and practicing Tai Chi. Descriptive data analysis was employed to present the feasibility and acceptability outcomes. Content analysis was employed to analyze the data from the qualitative process evaluation. <b>Results:</b> A total of 72 breast cancer patients were successfully recruited over six months, with a recruitment rate of 79.1%, retention rate of 95.8%, and dropout rate of 4.2%. No missing data was found in the BFI, PSQI, or HADS-D. However, a notable number of missing values were found in the FACT-B, particularly for items related to sexual satisfaction. The Tai Chi intervention demonstrated a high level of feasibility, with an average adherence rate of 86.8%. Only eight participants reported minor discomforts, such as minor musculoskeletal discomfort and dizziness, but they were transient and manageable after stopping Tai Chi practice. Semi-structured interviews with 22 participants highlighted that Tai Chi was experienced to be generally convenient, energy-saving, and low intensity for FSDSC management. Participants also felt that the study questionnaires were comprehensible and straightforward. Many interviewees from the Tai Chi group reported perceiving favorable effects on FSDSC management, as well as overall functional health and well-being. <b>Conclusions:</b> The evidence-based Tai Chi intervention proved feasible, safe, and convenient as a non-pharmacological intervention for managing FSDSC in breast cancer patients. Future large-scale studies are needed to evaluate Tai Chi’s definite effects on improving FSDSC among breast cancer patients.https://www.mdpi.com/2039-4403/15/5/167Tai Chibreast neoplasmsymptom clusterfatiguesleep disturbancedepression
spellingShingle Li-Qun Yao
Tao Wang
Xian-Liang Liu
Jing-Yu (Benjamin) Tan
Feasibility and Acceptability of Using an Evidence-Based Tai Chi Intervention for Managing the Fatigue–Sleep Disturbance–Depression Symptom Cluster in Breast Cancer Patients
Nursing Reports
Tai Chi
breast neoplasm
symptom cluster
fatigue
sleep disturbance
depression
title Feasibility and Acceptability of Using an Evidence-Based Tai Chi Intervention for Managing the Fatigue–Sleep Disturbance–Depression Symptom Cluster in Breast Cancer Patients
title_full Feasibility and Acceptability of Using an Evidence-Based Tai Chi Intervention for Managing the Fatigue–Sleep Disturbance–Depression Symptom Cluster in Breast Cancer Patients
title_fullStr Feasibility and Acceptability of Using an Evidence-Based Tai Chi Intervention for Managing the Fatigue–Sleep Disturbance–Depression Symptom Cluster in Breast Cancer Patients
title_full_unstemmed Feasibility and Acceptability of Using an Evidence-Based Tai Chi Intervention for Managing the Fatigue–Sleep Disturbance–Depression Symptom Cluster in Breast Cancer Patients
title_short Feasibility and Acceptability of Using an Evidence-Based Tai Chi Intervention for Managing the Fatigue–Sleep Disturbance–Depression Symptom Cluster in Breast Cancer Patients
title_sort feasibility and acceptability of using an evidence based tai chi intervention for managing the fatigue sleep disturbance depression symptom cluster in breast cancer patients
topic Tai Chi
breast neoplasm
symptom cluster
fatigue
sleep disturbance
depression
url https://www.mdpi.com/2039-4403/15/5/167
work_keys_str_mv AT liqunyao feasibilityandacceptabilityofusinganevidencebasedtaichiinterventionformanagingthefatiguesleepdisturbancedepressionsymptomclusterinbreastcancerpatients
AT taowang feasibilityandacceptabilityofusinganevidencebasedtaichiinterventionformanagingthefatiguesleepdisturbancedepressionsymptomclusterinbreastcancerpatients
AT xianliangliu feasibilityandacceptabilityofusinganevidencebasedtaichiinterventionformanagingthefatiguesleepdisturbancedepressionsymptomclusterinbreastcancerpatients
AT jingyubenjamintan feasibilityandacceptabilityofusinganevidencebasedtaichiinterventionformanagingthefatiguesleepdisturbancedepressionsymptomclusterinbreastcancerpatients