Advances in Etiology of High Incidence of Thyroid Cancer in Women

Thyroid cancer is the only non reproductive tumor that mainly occurs in women. The morbidity rate of female thyroid cancer is three times higher than that of male thyroid cancer. However, the existing studies have not systematically summarized the factors that contribute to the high incidence of thy...

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Main Authors: TAN Meijuan, YANG Shijie, LIU Zhenzuan, LIU Yumeng, XU Xiequn
Format: Article
Language:zho
Published: Editorial Office of Medical Journal of Peking Union Medical College Hospital 2024-10-01
Series:Xiehe Yixue Zazhi
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Online Access:https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0525
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author TAN Meijuan
YANG Shijie
LIU Zhenzuan
LIU Yumeng
XU Xiequn
author_facet TAN Meijuan
YANG Shijie
LIU Zhenzuan
LIU Yumeng
XU Xiequn
author_sort TAN Meijuan
collection DOAJ
description Thyroid cancer is the only non reproductive tumor that mainly occurs in women. The morbidity rate of female thyroid cancer is three times higher than that of male thyroid cancer. However, the existing studies have not systematically summarized the factors that contribute to the high incidence of thyroid cancer in women. This paper reviews all the literatures that mention the high incidence of thyroid cancer in women, and sorts out the main reasons, such as estrogen, obesity, reproductive factors, oxidation antioxidant system imbalance, X chromosome, etc., which are the main reasons for the current research finding that the incidence rate of thyroid cancer in women is higher than that in men. This paper makes a vivid graphic analysis and summary of the reasons, providing a research direction for future researchers to research on gender duality of thyroid cancer, and providing a certain reference for the clinical diagnosis and treatment of gender differences in thyroid cancer.
format Article
id doaj-art-229cd57f18d141b4b7da9b32e8ceab1c
institution DOAJ
issn 1674-9081
language zho
publishDate 2024-10-01
publisher Editorial Office of Medical Journal of Peking Union Medical College Hospital
record_format Article
series Xiehe Yixue Zazhi
spelling doaj-art-229cd57f18d141b4b7da9b32e8ceab1c2025-08-20T02:58:21ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812024-10-0116495796310.12290/xhyxzz.2024-0525Advances in Etiology of High Incidence of Thyroid Cancer in WomenTAN Meijuan0YANG Shijie1LIU Zhenzuan2LIU Yumeng3XU Xiequn4Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaCancer Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100029, ChinaDepartment of Histology and Embryology, School of Medicine, Shihezi University, Shihezi, Xinjiang 832003, ChinaDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaThyroid cancer is the only non reproductive tumor that mainly occurs in women. The morbidity rate of female thyroid cancer is three times higher than that of male thyroid cancer. However, the existing studies have not systematically summarized the factors that contribute to the high incidence of thyroid cancer in women. This paper reviews all the literatures that mention the high incidence of thyroid cancer in women, and sorts out the main reasons, such as estrogen, obesity, reproductive factors, oxidation antioxidant system imbalance, X chromosome, etc., which are the main reasons for the current research finding that the incidence rate of thyroid cancer in women is higher than that in men. This paper makes a vivid graphic analysis and summary of the reasons, providing a research direction for future researchers to research on gender duality of thyroid cancer, and providing a certain reference for the clinical diagnosis and treatment of gender differences in thyroid cancer.https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0525thyroid cancerfemaleestrogenobesityx chromosomeoxidation-antioxidant system
spellingShingle TAN Meijuan
YANG Shijie
LIU Zhenzuan
LIU Yumeng
XU Xiequn
Advances in Etiology of High Incidence of Thyroid Cancer in Women
Xiehe Yixue Zazhi
thyroid cancer
female
estrogen
obesity
x chromosome
oxidation-antioxidant system
title Advances in Etiology of High Incidence of Thyroid Cancer in Women
title_full Advances in Etiology of High Incidence of Thyroid Cancer in Women
title_fullStr Advances in Etiology of High Incidence of Thyroid Cancer in Women
title_full_unstemmed Advances in Etiology of High Incidence of Thyroid Cancer in Women
title_short Advances in Etiology of High Incidence of Thyroid Cancer in Women
title_sort advances in etiology of high incidence of thyroid cancer in women
topic thyroid cancer
female
estrogen
obesity
x chromosome
oxidation-antioxidant system
url https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0525
work_keys_str_mv AT tanmeijuan advancesinetiologyofhighincidenceofthyroidcancerinwomen
AT yangshijie advancesinetiologyofhighincidenceofthyroidcancerinwomen
AT liuzhenzuan advancesinetiologyofhighincidenceofthyroidcancerinwomen
AT liuyumeng advancesinetiologyofhighincidenceofthyroidcancerinwomen
AT xuxiequn advancesinetiologyofhighincidenceofthyroidcancerinwomen