Synthesis of Thienopyrimidines and their Antipsychotic Activity

A series of thienopyrimidines and related heterocycles were synthesized by refluxing related imidoyl chloride with primary and secondary amines under microwave irradiation and classical heating. The imidoyl chlorides were synthesized from corresponding cyclic imides with phosphorus oxychlorides unde...

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Main Authors: Chanchal Sharma, Swapnil Yerande, Rajashree Chavan, A. V. Bhosale
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2010/369141
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author Chanchal Sharma
Swapnil Yerande
Rajashree Chavan
A. V. Bhosale
author_facet Chanchal Sharma
Swapnil Yerande
Rajashree Chavan
A. V. Bhosale
author_sort Chanchal Sharma
collection DOAJ
description A series of thienopyrimidines and related heterocycles were synthesized by refluxing related imidoyl chloride with primary and secondary amines under microwave irradiation and classical heating. The imidoyl chlorides were synthesized from corresponding cyclic imides with phosphorus oxychlorides under microwave irradiation and classical heating. The structures of the compounds were confirmed by FT-IR, NMR. The synthesized compounds were screened for anti psychotic activity.
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issn 0973-4945
2090-9810
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series E-Journal of Chemistry
spelling doaj-art-2299b726cb494444a50109c6d7d968a12025-08-20T02:04:36ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017265566410.1155/2010/369141Synthesis of Thienopyrimidines and their Antipsychotic ActivityChanchal Sharma0Swapnil Yerande1Rajashree Chavan2A. V. Bhosale3Department of Pharmaceutical Chemistry, Poona District Education Association’s Seth Govind Raghunath, Sable College of Pharmacy, Saswad, Dist. Pune, Maharashtra-412 301, IndiaDepartment of Pharmaceutical Chemistry, Poona District Education Association’s Seth Govind Raghunath, Sable College of Pharmacy, Saswad, Dist. Pune, Maharashtra-412 301, IndiaDepartment of Pharmaceutical Chemistry, Poona District Education Association’s Seth Govind Raghunath, Sable College of Pharmacy, Saswad, Dist. Pune, Maharashtra-412 301, IndiaDepartment of Pharmaceutical Chemistry, Poona District Education Association’s Seth Govind Raghunath, Sable College of Pharmacy, Saswad, Dist. Pune, Maharashtra-412 301, IndiaA series of thienopyrimidines and related heterocycles were synthesized by refluxing related imidoyl chloride with primary and secondary amines under microwave irradiation and classical heating. The imidoyl chlorides were synthesized from corresponding cyclic imides with phosphorus oxychlorides under microwave irradiation and classical heating. The structures of the compounds were confirmed by FT-IR, NMR. The synthesized compounds were screened for anti psychotic activity.http://dx.doi.org/10.1155/2010/369141
spellingShingle Chanchal Sharma
Swapnil Yerande
Rajashree Chavan
A. V. Bhosale
Synthesis of Thienopyrimidines and their Antipsychotic Activity
E-Journal of Chemistry
title Synthesis of Thienopyrimidines and their Antipsychotic Activity
title_full Synthesis of Thienopyrimidines and their Antipsychotic Activity
title_fullStr Synthesis of Thienopyrimidines and their Antipsychotic Activity
title_full_unstemmed Synthesis of Thienopyrimidines and their Antipsychotic Activity
title_short Synthesis of Thienopyrimidines and their Antipsychotic Activity
title_sort synthesis of thienopyrimidines and their antipsychotic activity
url http://dx.doi.org/10.1155/2010/369141
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AT rajashreechavan synthesisofthienopyrimidinesandtheirantipsychoticactivity
AT avbhosale synthesisofthienopyrimidinesandtheirantipsychoticactivity