Evaluation of Children With Rotavirus Positive And Rotavirus Negative Diarrhea
Objective: Rotavirus is the most frequent cause of infectious acute gastroenteritis in children and may result in electrolyte imbalance, severe dehydration, hypovolemic shock, and death. Even though improved serological methods for definitive diagnosis exist, these methods may not always be easy to...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Istanbul University Press
2023-06-01
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| Series: | Çocuk Dergisi |
| Subjects: | |
| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/225303299C1448F6B65DF96E817BDAE9 |
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| Summary: | Objective: Rotavirus is the most frequent cause of infectious acute gastroenteritis in children and may result in electrolyte imbalance, severe dehydration, hypovolemic shock, and death. Even though improved serological methods for definitive diagnosis exist, these methods may not always be easy to reach. This study aims to evaluate the parameters that help the diagnosis of rotavirus gastroenteritis. Material and Methods: We retrospectively reviewed 1,539 children aged 1 month to 18 years who had been admitted to our hospital for acute gastroenteritis. Patients were divided into two groups: rotavirus positive and rotavirus negative. There were 745 patients in the RV-positive group and 794 patients in the RV-negative group. Results: The mean RBC (p=0.005), Hb (p<0.001), Htc (p<0.001), MCV (p<0.001), neutrophil (p=0.001), PLR (p=0.003), NLR (p<0.001), and ELR (p<0.001) levels were significantly lower in the RV-positive group. The mean PLT level (p=0.005) and the mean lymphocyte level (p<0.001) were significantly higher in the RV-positive group. Conclusion: Several hematological parameters were influenced in rotavirus gastroenteritis. RBC, Hb, Htc, MCV, the mean platelet level, the mean neutrophil level, the mean lymphocyte level, platelet /lymphocyte ratio, neutrophil/lymphocyte ratio, and the eosinophil/lymphocyte ratio could be supportive for rotavirus gastroenteritis. |
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| ISSN: | 1308-8491 |