Prevalence and comparison of severity of disease and complications among patients with night-time dyspnea in chronic obstructive pulmonary disease to those without night-time dyspnea
Background: Morning and night symptoms are prevalent and burdensome for patients with chronic obstructive pulmonary disease (COPD), compromising patients’ ability to perform tasks throughout the day. In particular, night symptoms are associated with worse health status and seem to be able to predict...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-04-01
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| Series: | MRIMS Journal of Health Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/mjhs.mjhs_89_23 |
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| Summary: | Background:
Morning and night symptoms are prevalent and burdensome for patients with chronic obstructive pulmonary disease (COPD), compromising patients’ ability to perform tasks throughout the day. In particular, night symptoms are associated with worse health status and seem to be able to predict future exacerbations.
Objective:
To study the prevalence of night-time dyspnea among individuals with COPD and comparison of severity of disease and complications.
Materials and Methods:
This was a prospective observational study among 80 diagnosed COPD patients. Severity of COPD was determined by spirometry according to Global Initiative for Obstructive Lung Diseases criteria with COPD Assessment Test scoring. The patients were then divided into study group (patients with night dyspnea) and control group (patients without night dyspnea) and were then followed up for every 3 months once for a period of 18 months.
Results:
The most common age at presentation was 60–69 years (35%). Males were nine times more affected than females. SpO2 at rest was significantly more in those without night dyspnea. Prevalence of night dyspnea was 38.8%. Severe and very severe disease, number of exacerbations > two, and getting admitted to hospital for > once were significantly more in night dyspnea patients (P < 0.05). During follow-up period, total seven patients died. Among them five died in those with night dyspnea compared to only two in those without night dyspnea. Kaplan–Meier estimate indicated that survival rate for night dyspnea patients was 0.039% and for no night dyspnea patients was 6.5%.
Conclusion:
The prevalence of night dyspnea was high and Night-time dyspnea is a marker of poor prognosis with regard to exacerbations, hospital admissions and survival. |
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| ISSN: | 2321-7006 2321-7294 |