REV-ERBα inhibitor rescues MPTP/MPP+-induced ferroptosis of dopaminergic neuron through regulating FASN/SCD1 signaling pathway

REV-ERBα inhibitor rescues MPTP/MPP+-induced ferroptosis of dopaminergic neuron through regulating FASN/SCD1 signaling pathway

Circadian disruption is a risk factor for Parkinson's disease (PD). Ferroptosis, a cellular death process, assumes a pivotal role in the degeneration of dopaminergic neurons in PD. Despite its significance, the potential contribution of circadian clock proteins to PD through the modulation of f...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaoyu Wang, Mingmei Wang, Hui Zhi, Jingwei Li, Dongkai Guo
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Heliyon
Subjects:
REV-ERBα
Ferroptosis
GPX4
FASN
SCD1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024164195
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items