Caveolin 1 in bovine liver is associated with fatty acid–induced lipid accumulation and the endoplasmic reticulum unfolded protein response: Role in fatty liver development

Caveolin 1 in bovine liver is associated with fatty acid–induced lipid accumulation and the endoplasmic reticulum unfolded protein response: Role in fatty liver development

ABSTRACT: Disruption of endoplasmic reticulum (ER) homeostasis (i.e., ER stress) is intrinsically linked with lipid metabolism disorders in dairy cows. Caveolin 1 (CAV1) is a ubiquitously expressed membrane-associated scaffolding protein involved in regulating the secretory pathway within the ER. Wh...

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Bibliographic Details
Main Authors: Ming Li, Bichen Zhao, Jingyi Wang, Huijing Zhang, Yue Yang, Shihao Song, Androniki Psifidi, Wenda Wu, Juan J. Loor, Chuang Xu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Dairy Science
Subjects:
fatty liver cows
free fatty acids
unfolded protein response
lipid accumulation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030224011780
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