Antibacterial, Antifungal, and Insecticidal Potentials of Oxalis corniculata and Its Isolated Compounds

Oxalis corniculata is a common medicinal plant widely used against numerous infectious diseases. The agrochemical potential of methanolic extract, n-hexane, chloroform, ethyl acetate, and n-butanol fractions were assessed to measure the antibacterial, antifungal, and insecticidal activities of the p...

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Main Authors: Azizur Rehman, Ali Rehman, Ijaz Ahmad
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2015/842468
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author Azizur Rehman
Ali Rehman
Ijaz Ahmad
author_facet Azizur Rehman
Ali Rehman
Ijaz Ahmad
author_sort Azizur Rehman
collection DOAJ
description Oxalis corniculata is a common medicinal plant widely used against numerous infectious diseases. The agrochemical potential of methanolic extract, n-hexane, chloroform, ethyl acetate, and n-butanol fractions were assessed to measure the antibacterial, antifungal, and insecticidal activities of the plant. The crude, chloroform, and n-butanol soluble fractions showed excellent activities against Escherichia coli, Shigella dysenteriae, Salmonella typhi, and Bacillus subtilis but have no activity against Staphylococcus aureus. Similarly the crude, n-hexane, and chloroform fractions were also found to have significant activity against fungal strains including Fusarium solani, Aspergillus flexneri, and Aspergillus flavus and have no activity against Aspergillus niger. Chemical pesticides have shown very good results at the beginning, but with the passage of time the need was realized to use the natural plant sources for the safe control of insects. The current study will provide minor contribution towards it. High mortality rate was recorded for the crude extract and chloroform fraction against Tribolium castaneum. The two isolated compounds 5-hydroxy-6,7,8,4′-tetramethoxyflavone (1) and 5,7,4′-trihydroxy-6,8-dimethoxyflavone (2) were evaluated for antibacterial, antifungal, and insecticidal activities. The results showed that compound 2 was more active than compound 1 against the tested bacterial strains and insects.
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spelling doaj-art-22781dadcaae4f39aa545bfc130d397b2025-02-03T01:11:12ZengWileyInternational Journal of Analytical Chemistry1687-87601687-87792015-01-01201510.1155/2015/842468842468Antibacterial, Antifungal, and Insecticidal Potentials of Oxalis corniculata and Its Isolated CompoundsAzizur Rehman0Ali Rehman1Ijaz Ahmad2Department of Chemistry, Kohat University of Science & Technology (KUST), Khyber Pakhtunkhwa, Kohat 26000, PakistanDepartment of Chemistry, Kohat University of Science & Technology (KUST), Khyber Pakhtunkhwa, Kohat 26000, PakistanDepartment of Chemistry, Kohat University of Science & Technology (KUST), Khyber Pakhtunkhwa, Kohat 26000, PakistanOxalis corniculata is a common medicinal plant widely used against numerous infectious diseases. The agrochemical potential of methanolic extract, n-hexane, chloroform, ethyl acetate, and n-butanol fractions were assessed to measure the antibacterial, antifungal, and insecticidal activities of the plant. The crude, chloroform, and n-butanol soluble fractions showed excellent activities against Escherichia coli, Shigella dysenteriae, Salmonella typhi, and Bacillus subtilis but have no activity against Staphylococcus aureus. Similarly the crude, n-hexane, and chloroform fractions were also found to have significant activity against fungal strains including Fusarium solani, Aspergillus flexneri, and Aspergillus flavus and have no activity against Aspergillus niger. Chemical pesticides have shown very good results at the beginning, but with the passage of time the need was realized to use the natural plant sources for the safe control of insects. The current study will provide minor contribution towards it. High mortality rate was recorded for the crude extract and chloroform fraction against Tribolium castaneum. The two isolated compounds 5-hydroxy-6,7,8,4′-tetramethoxyflavone (1) and 5,7,4′-trihydroxy-6,8-dimethoxyflavone (2) were evaluated for antibacterial, antifungal, and insecticidal activities. The results showed that compound 2 was more active than compound 1 against the tested bacterial strains and insects.http://dx.doi.org/10.1155/2015/842468
spellingShingle Azizur Rehman
Ali Rehman
Ijaz Ahmad
Antibacterial, Antifungal, and Insecticidal Potentials of Oxalis corniculata and Its Isolated Compounds
International Journal of Analytical Chemistry
title Antibacterial, Antifungal, and Insecticidal Potentials of Oxalis corniculata and Its Isolated Compounds
title_full Antibacterial, Antifungal, and Insecticidal Potentials of Oxalis corniculata and Its Isolated Compounds
title_fullStr Antibacterial, Antifungal, and Insecticidal Potentials of Oxalis corniculata and Its Isolated Compounds
title_full_unstemmed Antibacterial, Antifungal, and Insecticidal Potentials of Oxalis corniculata and Its Isolated Compounds
title_short Antibacterial, Antifungal, and Insecticidal Potentials of Oxalis corniculata and Its Isolated Compounds
title_sort antibacterial antifungal and insecticidal potentials of oxalis corniculata and its isolated compounds
url http://dx.doi.org/10.1155/2015/842468
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