A Case of a Rapidly Progressive Small Bowel Lymphoma with High Ki-67 Expression

Primary intestinal lymphoma is a rare disease. It accounts for approximately 1∼4% of gastrointestinal malignancy. Extranodal lymphoma of the intestine mainly arises from B cells. Diffuse large B-cell lymphoma is the most common type of the disease. Approximately 40% of intestinal lymphoma can be cur...

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Main Authors: Jiyeon Yoo, Hee Jun Kang, Hyungkeun Kim, Sujeong Han, Seung Hyun Oh, Sung Hoon Jung, Jung Hwan Oh, Eun Jung Jeon
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2017-03-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Subjects:
Online Access:http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.1.49
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author Jiyeon Yoo
Hee Jun Kang
Hyungkeun Kim
Sujeong Han
Seung Hyun Oh
Sung Hoon Jung
Jung Hwan Oh
Eun Jung Jeon
author_facet Jiyeon Yoo
Hee Jun Kang
Hyungkeun Kim
Sujeong Han
Seung Hyun Oh
Sung Hoon Jung
Jung Hwan Oh
Eun Jung Jeon
author_sort Jiyeon Yoo
collection DOAJ
description Primary intestinal lymphoma is a rare disease. It accounts for approximately 1∼4% of gastrointestinal malignancy. Extranodal lymphoma of the intestine mainly arises from B cells. Diffuse large B-cell lymphoma is the most common type of the disease. Approximately 40% of intestinal lymphoma can be cured, while 60% have varied disease progression. Ki-67 proliferation has been recently used as an index of cell growth to predict the progression of the disease. Reported herein is a case of a rapidly progressive small bowel diffuse large B-cell lymphoma in a 51-year-old man with a high Ki-67 expression level. He visited the emergency department because of hematochezia. Abdominal computed tomography revealed distal small bowel segmental wall thickening. He underwent operation due to spontaneous small bowel perforation. The result of the pathological examination of the resected specimen was compatible with diffuse large B-cell lymphoma. The Ki-67 index within 5 months was 90%.
format Article
id doaj-art-226b1eaacc1f45c6bcb3cdd3640d5e43
institution Kabale University
issn 1738-3331
language English
publishDate 2017-03-01
publisher Korean College of Helicobacter and Upper Gastrointestinal Research
record_format Article
series The Korean Journal of Helicobacter and Upper Gastrointestinal Research
spelling doaj-art-226b1eaacc1f45c6bcb3cdd3640d5e432025-08-20T03:33:18ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312017-03-01171495310.7704/kjhugr.2017.17.1.49kjhugr.2017.17.1.49A Case of a Rapidly Progressive Small Bowel Lymphoma with High Ki-67 ExpressionJiyeon Yoo0Hee Jun Kang1Hyungkeun Kim2Sujeong Han3Seung Hyun Oh4Sung Hoon Jung5Jung Hwan Oh6Eun Jung Jeon7Department of Internal Medicine, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Internal Medicine, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Internal Medicine, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Internal Medicine, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Internal Medicine, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Internal Medicine, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Internal Medicine, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Internal Medicine, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaPrimary intestinal lymphoma is a rare disease. It accounts for approximately 1∼4% of gastrointestinal malignancy. Extranodal lymphoma of the intestine mainly arises from B cells. Diffuse large B-cell lymphoma is the most common type of the disease. Approximately 40% of intestinal lymphoma can be cured, while 60% have varied disease progression. Ki-67 proliferation has been recently used as an index of cell growth to predict the progression of the disease. Reported herein is a case of a rapidly progressive small bowel diffuse large B-cell lymphoma in a 51-year-old man with a high Ki-67 expression level. He visited the emergency department because of hematochezia. Abdominal computed tomography revealed distal small bowel segmental wall thickening. He underwent operation due to spontaneous small bowel perforation. The result of the pathological examination of the resected specimen was compatible with diffuse large B-cell lymphoma. The Ki-67 index within 5 months was 90%.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.1.49Intestine, smallKi-67Lymphoma, large B-cell, diffuse
spellingShingle Jiyeon Yoo
Hee Jun Kang
Hyungkeun Kim
Sujeong Han
Seung Hyun Oh
Sung Hoon Jung
Jung Hwan Oh
Eun Jung Jeon
A Case of a Rapidly Progressive Small Bowel Lymphoma with High Ki-67 Expression
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Intestine, small
Ki-67
Lymphoma, large B-cell, diffuse
title A Case of a Rapidly Progressive Small Bowel Lymphoma with High Ki-67 Expression
title_full A Case of a Rapidly Progressive Small Bowel Lymphoma with High Ki-67 Expression
title_fullStr A Case of a Rapidly Progressive Small Bowel Lymphoma with High Ki-67 Expression
title_full_unstemmed A Case of a Rapidly Progressive Small Bowel Lymphoma with High Ki-67 Expression
title_short A Case of a Rapidly Progressive Small Bowel Lymphoma with High Ki-67 Expression
title_sort case of a rapidly progressive small bowel lymphoma with high ki 67 expression
topic Intestine, small
Ki-67
Lymphoma, large B-cell, diffuse
url http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.1.49
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