Nilotinib attenuates vascular pathology in experimental cerebral malaria

Nilotinib attenuates vascular pathology in experimental cerebral malaria

Abstract: Cerebral malaria (CM), a life-threatening complication of Plasmodium falciparum infection, is characterized by the sequestration of infected erythrocytes in the brain microvasculature. Our study investigated the potential of repurposing tyrosine kinase inhibitors targeting BCR-ABL1 (BCR-AB...

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Main Authors: Luana S. Ortolan, Priyanka Bansal, Veronica I. Primavera, Rodrigo J. R. X. Freitas, Ling Wei, Sabrina Epiphanio, Alexis Kaushansky, Joseph D. Smith
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925001296
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