Challenges in Diagnosing Necrotizing Sarcoid Granulomatosis: The First Case Reported From Indonesia

Necrotizing sarcoid granulomatosis (NSG) is a rare disease characterized by granulomatous and necrotic features as well as vasculitis, and it primarily affects the lungs, with occasional extrapulmonary manifestations. The first documented case was in Jakarta, Indonesia. A 71-year-old male presented...

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Main Authors: Gurmeet Singh, Ramadhan Karsono, Soedarman Sjamsoe, Muhammad Rizki Triono, Rina La Distia Nora, Devi Felicia, Fajar Lamhot Gultom, Daniel Ruslim, Arif Sejati, Ralph Girson Gunarsa, Ceva Wicaksono Pitoyo, Cleopas Martin Rumende
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/carm/3219868
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Summary:Necrotizing sarcoid granulomatosis (NSG) is a rare disease characterized by granulomatous and necrotic features as well as vasculitis, and it primarily affects the lungs, with occasional extrapulmonary manifestations. The first documented case was in Jakarta, Indonesia. A 71-year-old male presented with prolonged fever, a neck mass, and multiple mediastinal lymphadenopathy. The disease was initially suspected as lung tuberculosis, but a surgical biopsy of the left thyroid lobe confirmed the NSG pattern. Treatment with oral prednisolone led to positive outcomes, as evidenced by radiological improvement at the 3-month follow-up. This case report aims to emphasize the challenges and the importance of clinician awareness in diagnosing NSG.
ISSN:1687-9635