A-type lamins maintain the positional stability of DNA damage repair foci in mammalian nuclei.

A-type lamins maintain the positional stability of DNA damage repair foci in mammalian nuclei.

A-type lamins encoded by LMNA form a structural fibrillar meshwork within the mammalian nucleus. How this nuclear organization may influence the execution of biological processes involving DNA transactions remains unclear. Here, we characterize changes in the dynamics and biochemical interactions of...

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Main Authors: Robert Mahen, Hiroyoshi Hattori, Miyoung Lee, Pooja Sharma, Anand D Jeyasekharan, Ashok R Venkitaraman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0061893&type=printable
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