HIV reservoir in HIV patients

An HIV reservoir is a collection of HIV DNA in target cells in an HIV-infected person. HIV reservoir in patients with HIV infection prevents eradication of the pathogen and cure of the disease. The review presents published data on the structure of HIV reservoir, its formation and change of its size...

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Main Authors: E. I. Veselova, G. D. Kaminskiy, A. G. Samoylova, I. A. Vasilyeva
Format: Article
Language:Russian
Published: New Terra Publishing House 2019-05-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/1270
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author E. I. Veselova
G. D. Kaminskiy
A. G. Samoylova
I. A. Vasilyeva
author_facet E. I. Veselova
G. D. Kaminskiy
A. G. Samoylova
I. A. Vasilyeva
author_sort E. I. Veselova
collection DOAJ
description An HIV reservoir is a collection of HIV DNA in target cells in an HIV-infected person. HIV reservoir in patients with HIV infection prevents eradication of the pathogen and cure of the disease. The review presents published data on the structure of HIV reservoir, its formation and change of its size at different stages of the disease, depending on the time of treatment initiation. The article demonstrates the results of studies that investigated the effect of antiretroviral therapy on the size of the reservoir and the ability to use the size of HIV reservoir as a clinically significant indicator of the course of the disease. The current strategies for influencing on HIV reservoir are considered, the ultimate goal of which is recovery from HIV infection.
format Article
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institution OA Journals
issn 2075-1230
2542-1506
language Russian
publishDate 2019-05-01
publisher New Terra Publishing House
record_format Article
series Туберкулез и болезни лёгких
spelling doaj-art-22503deeb5984f51b7cb2694e1d4ec862025-08-20T01:47:52ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062019-05-01975505710.21292/2075-1230-2019-97-5-50-571270HIV reservoir in HIV patientsE. I. Veselova0G. D. Kaminskiy1A. G. Samoylova2I. A. Vasilyeva3National Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesAn HIV reservoir is a collection of HIV DNA in target cells in an HIV-infected person. HIV reservoir in patients with HIV infection prevents eradication of the pathogen and cure of the disease. The review presents published data on the structure of HIV reservoir, its formation and change of its size at different stages of the disease, depending on the time of treatment initiation. The article demonstrates the results of studies that investigated the effect of antiretroviral therapy on the size of the reservoir and the ability to use the size of HIV reservoir as a clinically significant indicator of the course of the disease. The current strategies for influencing on HIV reservoir are considered, the ultimate goal of which is recovery from HIV infection.https://www.tibl-journal.com/jour/article/view/1270hiv infectionhiv reservoirstrategies on hiv reservoir eradication
spellingShingle E. I. Veselova
G. D. Kaminskiy
A. G. Samoylova
I. A. Vasilyeva
HIV reservoir in HIV patients
Туберкулез и болезни лёгких
hiv infection
hiv reservoir
strategies on hiv reservoir eradication
title HIV reservoir in HIV patients
title_full HIV reservoir in HIV patients
title_fullStr HIV reservoir in HIV patients
title_full_unstemmed HIV reservoir in HIV patients
title_short HIV reservoir in HIV patients
title_sort hiv reservoir in hiv patients
topic hiv infection
hiv reservoir
strategies on hiv reservoir eradication
url https://www.tibl-journal.com/jour/article/view/1270
work_keys_str_mv AT eiveselova hivreservoirinhivpatients
AT gdkaminskiy hivreservoirinhivpatients
AT agsamoylova hivreservoirinhivpatients
AT iavasilyeva hivreservoirinhivpatients