Inhibition of miMOMP-induced SASP to combat age-related disease
Cellular senescence, first described in 1961, was initially observed in normal human fibroblasts that ceased proliferating after a finite number of divisions in culture. This process is triggered by various stimuli, including oxidative stress, chromatin modifications and oncogene activation, charact...
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Main Authors: | Xiaoli Liao, Zhennan Guo, Mouhai He, Yichun Zhang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-01-01
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Series: | Frontiers in Aging |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fragi.2025.1505063/full |
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