In vitro generation of a ureteral organoid from pluripotent stem cells

Abstract The ureter is the outlet for urine produced by the kidney. Recent advances in stem cell biology have enabled the in vitro generation of kidney organoids from pluripotent stem cells (PSCs), but they lack the ureter, which hinders the smooth drainage of urine. By mimicking the in vivo develop...

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Bibliographic Details
Main Authors: Yutaro Ibi, Koichiro Miike, Tomoko Ohmori, Chen-Leng Cai, Shunsuke Tanigawa, Ryuichi Nishinakamura
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60693-6
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