Superparamagnetic hydrogels: Precision-driven platforms for biomedicine, robotics, and environmental remediation

Hydrogels are widely recognized for their biocompatibility and structural adaptability in regenerative medicine and three-dimensional (3D) bioprinting, yet their inherent static nature fundamentally limits applications demanding dynamic spatiotemporal control. The incorporation of superparamagnetic...

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Bibliographic Details
Main Authors: Huaibin Wang, Yingying Hou, Long Chen, Weihong Mo, Leyan Xuan, Jialin Wu, Jie Wang, Maobin Xie, Shufang Wang, Guosheng Tang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-06-01
Series:Biomedical Technology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949723X25000169
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Summary:Hydrogels are widely recognized for their biocompatibility and structural adaptability in regenerative medicine and three-dimensional (3D) bioprinting, yet their inherent static nature fundamentally limits applications demanding dynamic spatiotemporal control. The incorporation of superparamagnetic iron oxide nanoparticles (SPIONs) addresses this issue. The incorporation of SPIONs enables real-time programmable manipulation through magnetic field gradients. This amalgamation not only endows hydrogels with abilities such as magnetic propulsion, positioning, magnetoguidance, movement, and levitation, typical of magnetic materials, but also introduces novel functionalities like responsiveness to thermal effects and enhanced adsorption capabilities. This review delves into the transformative potential unlocked by the integration of SPIONs into hydrogels, showcasing their unique functional enhancements and targeted applications in robotics, precision medicine, and wastewater treatment.
ISSN:2949-723X