Specific activation of cGAS-STING pathway by manganese-doped bioactive glasses for boosting systemic tumor immunotherapy

Specific activation of cGAS-STING pathway by manganese-doped bioactive glasses for boosting systemic tumor immunotherapy

The recurrence and metastasis of renal cell carcinoma present significant challenges in clinical settings, necessitating the urgent development of strategies to enhance the efficacy of kidney cancer treatments. In this study, we designed and developed a manganese-doped bioactive glass-based (Mn-MBG)...

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Bibliographic Details
Main Authors: Zhaolin Yang, Jiale Zhou, Xinrui Wu, Sian Zhou, Wei Xue, Jiahua Pan, Yonghui Chen, Xiaorong Wu
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Materials & Design
Subjects:
Renal cell carcinoma
Mn-MBG
cGAS-STING
Immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127525001844
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