Integrated proteomics and transcriptomics analysis reveals key regulatory genes between ER-positive/PR-positive and ER-positive/PR-negative breast cancer

Integrated proteomics and transcriptomics analysis reveals key regulatory genes between ER-positive/PR-positive and ER-positive/PR-negative breast cancer

Abstract Purpose Hormone receptor-positive breast cancer is characterized by the expression of estrogen receptor (ER) or progesterone receptor (PR), it is generally associated with less aggressive clinical features and more favorable prognostic outcomes, primarily due to the effectiveness of endocri...

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Bibliographic Details
Main Authors: Zhengjia Lu, Jiao Yang, Yang Feng, Jia Ming
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Estrogen receptor
Progesterone receptor
Proteomic analysis
Prognosis
Online Access:https://doi.org/10.1186/s12885-025-14451-y
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