Fructose induces metabolic reprogramming in liver cancer cells, promoting aggressiveness and chemotherapy resistance

Fructose induces metabolic reprogramming in liver cancer cells, promoting aggressiveness and chemotherapy resistance

Aim: Fructose is a highly lipogenic compound related to the onset of steatosis, its progression to steatohepatitis, and the eventual initiation of hepatocellular carcinoma (HCC). One of the cancer hallmarks is the metabolic adaptation to the environmental sources; however, this characteristic could...

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Main Authors: Lisette Chávez-Rodríguez, Alejandro Escobedo-Calvario, Verena Jendrossek, Johann Matschke, Maike Busch, Nicole Dünker, Moisés Vergara-Mendoza, Verónica Souza-Arroyo, Leticia Bucio-Ortiz, Roxana U. Miranda-Labra, Araceli Páez-Arenas, María Concepción Gutiérrez-Ruiz, Diego F. Calvisi, Luis E. Gomez-Quiroz
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2025-04-01
Series:Exploration of Digestive Diseases
Subjects:
fructose
metabolism
hepatocellular carcinoma
masld
Online Access:https://www.explorationpub.com/uploads/Article/A100572/100572.pdf
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