Intratracheal Administration of Nanoplastics With Varying Surface Hydrophobicity Results in Coarsely Vacuolated Alveolar Macrophages, Transient Respiratory Inflammation, and Mild Collagen Deposition

Intratracheal Administration of Nanoplastics With Varying Surface Hydrophobicity Results in Coarsely Vacuolated Alveolar Macrophages, Transient Respiratory Inflammation, and Mild Collagen Deposition

ABSTRACT Inhalation of biopersistent nanoplastics may have adverse effects on lung health. By varying the acetate content of poly(vinyl acetate‐co‐alcohol) (PVAc), model nanoplastics with different surface hydrophobicity can be produced to study the effects of nanoplastic hydrophobicity in the lung....

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Bibliographic Details
Main Authors: Anna Babin Morgan, Yanira Riffo‐Vasquez, Aateka Bodhaniya, Stuart A. Jones, Ben Forbes, Kavitha Sunassee, Rafael T. M. deRosales, Stephanie Wright, Clive Page, Lea Ann Dailey
Format: Article
Language:English
Published: Wiley-VCH 2025-07-01
Series:Nano Select
Subjects:
hydrophobicity
inflammation
lung
macrophages
nanoplastics
Online Access:https://doi.org/10.1002/nano.202400154
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