Fabrication of Pterocephalus nestorianus Nab. based phyto nanoliposomes and investigating their bioactivities and blood reducing cholesterol ability
The aqueous extract of Pterocephalus nestorianus Nab. plant was used for the simple, green, economic and fast synthesis of nanoliposomes capturing the plant phytochemicals into their inner sell at different compositions. The phyto-loaded nanoliposomes (phyto-NLs or PNLs) then were structurally eluci...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Results in Chemistry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625004266 |
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| author | Abdulbast Ali Khafoor Aiman Amjad Al-Delawi Ayoub Sabir Karim S. Mohammad Sajadi |
| author_facet | Abdulbast Ali Khafoor Aiman Amjad Al-Delawi Ayoub Sabir Karim S. Mohammad Sajadi |
| author_sort | Abdulbast Ali Khafoor |
| collection | DOAJ |
| description | The aqueous extract of Pterocephalus nestorianus Nab. plant was used for the simple, green, economic and fast synthesis of nanoliposomes capturing the plant phytochemicals into their inner sell at different compositions. The phyto-loaded nanoliposomes (phyto-NLs or PNLs) then were structurally elucidated using TEM (Transmission Electron Microscopy), FE-SEM (Field Emissions Scanning Electron Microscopy), DLS (Dynamic Light Scattering) and FTIR (Fourier Transform Infrared Spectroscopy) which revealed the well formation of spherical homogeneous PNLs in size ranging 20 to 80 nm loaded by phytochemicals. Also, Zeta-potential (z-potential) analysis was used for all different compositions of PNLs to detect the most stable one. Investigation of the bioactivity of PNLs showed a very good results for their antioxidant activities and antibacterial potential against dangerous pathogenic bacteria. Furthermore, due to the capturing of plant phytochemicals inside the nanoliposomes, the effect of PNLs was studied on reducing blood cholesterol of rat models which demonstrated very satisfactorily results and showed it can be a possible treatment for this problem. |
| format | Article |
| id | doaj-art-2228849991e84cf796426ec08b4d3cbf |
| institution | DOAJ |
| issn | 2211-7156 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj-art-2228849991e84cf796426ec08b4d3cbf2025-08-20T03:01:46ZengElsevierResults in Chemistry2211-71562025-07-011610244310.1016/j.rechem.2025.102443Fabrication of Pterocephalus nestorianus Nab. based phyto nanoliposomes and investigating their bioactivities and blood reducing cholesterol abilityAbdulbast Ali Khafoor0Aiman Amjad Al-Delawi1Ayoub Sabir Karim2S. Mohammad Sajadi3Erbil Polytechnic University-Soran Technical College, Erbil, Kurdistan Region, IraqDepartment of Community Health Nursing, Cihan University-Erbil, KRG, IraqPhysics Department, College of Education, Salahaddin University-, Erbil 44002, Iraqi Kurdistan Region, IraqDepartment of Chemistry, Payem e Noor University, Saqqez Branch, Saqqez, Iran; Corresponding author.The aqueous extract of Pterocephalus nestorianus Nab. plant was used for the simple, green, economic and fast synthesis of nanoliposomes capturing the plant phytochemicals into their inner sell at different compositions. The phyto-loaded nanoliposomes (phyto-NLs or PNLs) then were structurally elucidated using TEM (Transmission Electron Microscopy), FE-SEM (Field Emissions Scanning Electron Microscopy), DLS (Dynamic Light Scattering) and FTIR (Fourier Transform Infrared Spectroscopy) which revealed the well formation of spherical homogeneous PNLs in size ranging 20 to 80 nm loaded by phytochemicals. Also, Zeta-potential (z-potential) analysis was used for all different compositions of PNLs to detect the most stable one. Investigation of the bioactivity of PNLs showed a very good results for their antioxidant activities and antibacterial potential against dangerous pathogenic bacteria. Furthermore, due to the capturing of plant phytochemicals inside the nanoliposomes, the effect of PNLs was studied on reducing blood cholesterol of rat models which demonstrated very satisfactorily results and showed it can be a possible treatment for this problem.http://www.sciencedirect.com/science/article/pii/S2211715625004266Pterocephalus nestorianusPhyto-nanoliposomeBioactivityBlood cholesterol |
| spellingShingle | Abdulbast Ali Khafoor Aiman Amjad Al-Delawi Ayoub Sabir Karim S. Mohammad Sajadi Fabrication of Pterocephalus nestorianus Nab. based phyto nanoliposomes and investigating their bioactivities and blood reducing cholesterol ability Results in Chemistry Pterocephalus nestorianus Phyto-nanoliposome Bioactivity Blood cholesterol |
| title | Fabrication of Pterocephalus nestorianus Nab. based phyto nanoliposomes and investigating their bioactivities and blood reducing cholesterol ability |
| title_full | Fabrication of Pterocephalus nestorianus Nab. based phyto nanoliposomes and investigating their bioactivities and blood reducing cholesterol ability |
| title_fullStr | Fabrication of Pterocephalus nestorianus Nab. based phyto nanoliposomes and investigating their bioactivities and blood reducing cholesterol ability |
| title_full_unstemmed | Fabrication of Pterocephalus nestorianus Nab. based phyto nanoliposomes and investigating their bioactivities and blood reducing cholesterol ability |
| title_short | Fabrication of Pterocephalus nestorianus Nab. based phyto nanoliposomes and investigating their bioactivities and blood reducing cholesterol ability |
| title_sort | fabrication of pterocephalus nestorianus nab based phyto nanoliposomes and investigating their bioactivities and blood reducing cholesterol ability |
| topic | Pterocephalus nestorianus Phyto-nanoliposome Bioactivity Blood cholesterol |
| url | http://www.sciencedirect.com/science/article/pii/S2211715625004266 |
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