A research on the mechanism of SERPINA3 promoting malignant progression and gemcitabine resistance of pancreatic cancer by inhibiting ferroptosis
Background and purpose: Members of the serine protease inhibitor (SERPIN) family can influence tumorigenesis, progression, and prognosis by modulating processes such as apoptosis, invasion, metastasis, and angiogenesis in tumor cells. However, their role in pancreatic cancer remains unclear. This st...
Saved in:
| Main Author: | HE Yuan, GUO Juncheng, YE Zhibin, WANG Xiaohu, LI Haonan, HUANG Jingbiao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Editorial Office of China Oncology
2025-06-01
|
| Series: | Zhongguo aizheng zazhi |
| Subjects: | |
| Online Access: | https://www.china-oncology.com/fileup/1007-3639/PDF/1752457546615-510644080.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
NCOA6 knockdown enhances RSL3-induced ferroptosis in pancreatic cancer cells and increases the sensitivity to gemcitabine
by: Jia Yuming, et al.
Published: (2025-03-01) -
TSPAN15 sustains ITGB1 stability to block gemcitabine-induced ferroptosis in pancreatic ductal adenocarcinoma through the FAK/AKT/Mtor-gpx4 cascade
by: Peng Nan, et al.
Published: (2025-09-01) -
Improved Antitumor Efficiency of N4-Tetradecyloxycarbonyl Gemcitabine-Loaded Liposomes for Pancreatic Cancer Chemotherapy
by: Wang D, et al.
Published: (2024-12-01) -
Exploring the impact of SerpinA3n deficiency on prion strains propagation
by: Fabio Moda, et al.
Published: (2025-08-01) -
Nab-Paclitaxel plus gemcitabine in patients with metastatic pancreatic adenocarcinoma: experience of use
by: Elena Ferris Villanueva, et al.
Published: (2015-02-01)