A case of esophageal carcinoma on esophageal varices treated by endoscopic submucosal dissection after endoscopic injection sclerotherapy
Abstract Esophageal varices (EVs) are often treated using endoscopic injection sclerotherapy. Endoscopic submucosal dissection (ESD) has been used for early esophageal epithelial neoplasia worldwide. We report a case of early esophageal squamous cell carcinoma (ESCC) that occurred over EVs, in which...
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Wiley
2023-04-01
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| Series: | DEN Open |
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| Online Access: | https://doi.org/10.1002/deo2.202 |
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| author | Kenichiro Nakachi Takao Maekita Hisanobu Deguchi Masatomo Kimura Mikitaka Iguchi Satoshi Yoshida Masayuki Kitano |
| author_facet | Kenichiro Nakachi Takao Maekita Hisanobu Deguchi Masatomo Kimura Mikitaka Iguchi Satoshi Yoshida Masayuki Kitano |
| author_sort | Kenichiro Nakachi |
| collection | DOAJ |
| description | Abstract Esophageal varices (EVs) are often treated using endoscopic injection sclerotherapy. Endoscopic submucosal dissection (ESD) has been used for early esophageal epithelial neoplasia worldwide. We report a case of early esophageal squamous cell carcinoma (ESCC) that occurred over EVs, in which the EVs were treated with endoscopic injection sclerotherapy before the early ESCC was treated with endoscopic submucosal dissection. Argon plasma coagulation was finally performed to prevent the recurrence of varices. No serious complications, such as severe bleeding or perforation, were observed. Histopathological examination revealed submucosal veins occluded with an organized thrombus for which endoscopic injection sclerotherapy with an intravariceal injection of sclerosant had been performed, but no fibrosis was observed outside the blood vessels. This explains that the injected sclerosant into EVs did not cause any tissue reaction like fibrosis in the submucosa surrounding the vein, which may have made endoscopic submucosal dissection safer and easier. Varices have not recurred, and ESCC has also not recurred for 5 years. We demonstrated a successful treatment of ESCC on EVs and no submucosal fibrosis other than inside the occluded vessels and verified it histologically. |
| format | Article |
| id | doaj-art-220acd9d225d47e3b45fbc412236a3fd |
| institution | DOAJ |
| issn | 2692-4609 |
| language | English |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj-art-220acd9d225d47e3b45fbc412236a3fd2025-08-20T03:10:01ZengWileyDEN Open2692-46092023-04-0131n/an/a10.1002/deo2.202A case of esophageal carcinoma on esophageal varices treated by endoscopic submucosal dissection after endoscopic injection sclerotherapyKenichiro Nakachi0Takao Maekita1Hisanobu Deguchi2Masatomo Kimura3Mikitaka Iguchi4Satoshi Yoshida5Masayuki Kitano6GastroenterologicalMedicine Kameda Medical Center Kamogawa Chiba JapanDepartment of Gastroenterology Wakayama Medical University Wakayama JapanInternal Medicine Nokami Kousei Sogo Hospital Wakayama JapanDepartment of Pathology Hashimoto Municipal Hospital Wakayama JapanDepartment of Gastroenterology Wakayama Medical University Wakayama JapanGastroenterological Medicine Hashimoto Municipal Hospital Wakayama JapanDepartment of Gastroenterology Wakayama Medical University Wakayama JapanAbstract Esophageal varices (EVs) are often treated using endoscopic injection sclerotherapy. Endoscopic submucosal dissection (ESD) has been used for early esophageal epithelial neoplasia worldwide. We report a case of early esophageal squamous cell carcinoma (ESCC) that occurred over EVs, in which the EVs were treated with endoscopic injection sclerotherapy before the early ESCC was treated with endoscopic submucosal dissection. Argon plasma coagulation was finally performed to prevent the recurrence of varices. No serious complications, such as severe bleeding or perforation, were observed. Histopathological examination revealed submucosal veins occluded with an organized thrombus for which endoscopic injection sclerotherapy with an intravariceal injection of sclerosant had been performed, but no fibrosis was observed outside the blood vessels. This explains that the injected sclerosant into EVs did not cause any tissue reaction like fibrosis in the submucosa surrounding the vein, which may have made endoscopic submucosal dissection safer and easier. Varices have not recurred, and ESCC has also not recurred for 5 years. We demonstrated a successful treatment of ESCC on EVs and no submucosal fibrosis other than inside the occluded vessels and verified it histologically.https://doi.org/10.1002/deo2.202early esophageal squamous cell carcinomaendoscopic injection sclerotherapyendoscopic submucosal dissectionesophageal varixesophagogastroduodenoscopy |
| spellingShingle | Kenichiro Nakachi Takao Maekita Hisanobu Deguchi Masatomo Kimura Mikitaka Iguchi Satoshi Yoshida Masayuki Kitano A case of esophageal carcinoma on esophageal varices treated by endoscopic submucosal dissection after endoscopic injection sclerotherapy DEN Open early esophageal squamous cell carcinoma endoscopic injection sclerotherapy endoscopic submucosal dissection esophageal varix esophagogastroduodenoscopy |
| title | A case of esophageal carcinoma on esophageal varices treated by endoscopic submucosal dissection after endoscopic injection sclerotherapy |
| title_full | A case of esophageal carcinoma on esophageal varices treated by endoscopic submucosal dissection after endoscopic injection sclerotherapy |
| title_fullStr | A case of esophageal carcinoma on esophageal varices treated by endoscopic submucosal dissection after endoscopic injection sclerotherapy |
| title_full_unstemmed | A case of esophageal carcinoma on esophageal varices treated by endoscopic submucosal dissection after endoscopic injection sclerotherapy |
| title_short | A case of esophageal carcinoma on esophageal varices treated by endoscopic submucosal dissection after endoscopic injection sclerotherapy |
| title_sort | case of esophageal carcinoma on esophageal varices treated by endoscopic submucosal dissection after endoscopic injection sclerotherapy |
| topic | early esophageal squamous cell carcinoma endoscopic injection sclerotherapy endoscopic submucosal dissection esophageal varix esophagogastroduodenoscopy |
| url | https://doi.org/10.1002/deo2.202 |
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