Intracranial Mesenchymal Chondrosarcoma: A Case Report

Abstract Primary intracranial mesenchymal chondrosarcoma is an extremely rare tumor. We present a case of primary intracranial mesenchymal chondrosarcoma in a young female who presented with headache, loss of vision, and one episode of convulsions associated with nausea and vomiting. MRI brain revea...

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Main Authors: Prachi Agrawal, Ajay Gupta, Shagun Juneja, Veena Gupta
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2015-03-01
Series:Indian Journal of Neurosurgery
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1548997
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author Prachi Agrawal
Ajay Gupta
Shagun Juneja
Veena Gupta
author_facet Prachi Agrawal
Ajay Gupta
Shagun Juneja
Veena Gupta
author_sort Prachi Agrawal
collection DOAJ
description Abstract Primary intracranial mesenchymal chondrosarcoma is an extremely rare tumor. We present a case of primary intracranial mesenchymal chondrosarcoma in a young female who presented with headache, loss of vision, and one episode of convulsions associated with nausea and vomiting. MRI brain revealed a large, well-marginated, lobulated, partially calcified, intensely enhancing lesion with a broad dural base in bilateral frontal regions with marked mass effect suggestive of meningioma. Bilateral frontal craniotomy with gross tumor excision was performed. Histopathology revealed mesenchymal chondrosarcoma. Adjuvant radiotherapy was delivered and patient is currently on follow-up. We emphasize that intracranial mesenchymal chondrosarcoma is a rare neoplasm and should be considered in the differential diagnoses of intracranial mass along with meningioma. Treatment of choice is surgery followed by adjuvant radiotherapy. We review the relevant literature and discuss the characteristics of this rare tumor.
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publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
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series Indian Journal of Neurosurgery
spelling doaj-art-22083d908c964fe595e0a2acc4e354952025-08-20T02:01:19ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Neurosurgery2277-954X2277-91672015-03-01040103103410.1055/s-0035-1548997Intracranial Mesenchymal Chondrosarcoma: A Case ReportPrachi Agrawal0Ajay Gupta1Shagun Juneja2Veena Gupta3Department of Radiotherapy, Safdarjung Hospital, New Delhi, IndiaDepartment of Radiotherapy, Safdarjung Hospital, New Delhi, IndiaDepartment of Radiotherapy, Safdarjung Hospital, New Delhi, IndiaDepartment of Radiotherapy, Safdarjung Hospital, New Delhi, IndiaAbstract Primary intracranial mesenchymal chondrosarcoma is an extremely rare tumor. We present a case of primary intracranial mesenchymal chondrosarcoma in a young female who presented with headache, loss of vision, and one episode of convulsions associated with nausea and vomiting. MRI brain revealed a large, well-marginated, lobulated, partially calcified, intensely enhancing lesion with a broad dural base in bilateral frontal regions with marked mass effect suggestive of meningioma. Bilateral frontal craniotomy with gross tumor excision was performed. Histopathology revealed mesenchymal chondrosarcoma. Adjuvant radiotherapy was delivered and patient is currently on follow-up. We emphasize that intracranial mesenchymal chondrosarcoma is a rare neoplasm and should be considered in the differential diagnoses of intracranial mass along with meningioma. Treatment of choice is surgery followed by adjuvant radiotherapy. We review the relevant literature and discuss the characteristics of this rare tumor.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1548997mesenchymal chondrosarcomaintracranialsurgeryradiotherapy
spellingShingle Prachi Agrawal
Ajay Gupta
Shagun Juneja
Veena Gupta
Intracranial Mesenchymal Chondrosarcoma: A Case Report
Indian Journal of Neurosurgery
mesenchymal chondrosarcoma
intracranial
surgery
radiotherapy
title Intracranial Mesenchymal Chondrosarcoma: A Case Report
title_full Intracranial Mesenchymal Chondrosarcoma: A Case Report
title_fullStr Intracranial Mesenchymal Chondrosarcoma: A Case Report
title_full_unstemmed Intracranial Mesenchymal Chondrosarcoma: A Case Report
title_short Intracranial Mesenchymal Chondrosarcoma: A Case Report
title_sort intracranial mesenchymal chondrosarcoma a case report
topic mesenchymal chondrosarcoma
intracranial
surgery
radiotherapy
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1548997
work_keys_str_mv AT prachiagrawal intracranialmesenchymalchondrosarcomaacasereport
AT ajaygupta intracranialmesenchymalchondrosarcomaacasereport
AT shagunjuneja intracranialmesenchymalchondrosarcomaacasereport
AT veenagupta intracranialmesenchymalchondrosarcomaacasereport