OBSTRUCTIVE SLEEP APNEA SYNDROME IN CHILDREN WITH TYPE II MUCOPOLYSACCHARIDOSIS (HUNTER SYNDROME)
17 children received cardiorespiratory monitoring in order to evaluate spread and dynamics of changes in the primary obstructive sleep apnea syndrome (OSAS) parameters at type II mucopolysaccharidosis. Mild OSAS [apnea/hypopnea index (AHI) – 1.5-5] was diagnosed in 4 patients (23.5%), moderate OSAS...
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| Language: | Russian |
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Union of pediatricians of Russia
2013-11-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/161 |
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| author | N. D. Vashakmadze L. S. Namazova-Baranova A. K. Gevorkyan V. V. Altunin L. M. Kuzenkova E. G. Chernavina M. A. Babaykina T. V. Podkletnova O. V. Kozhevnikova |
| author_facet | N. D. Vashakmadze L. S. Namazova-Baranova A. K. Gevorkyan V. V. Altunin L. M. Kuzenkova E. G. Chernavina M. A. Babaykina T. V. Podkletnova O. V. Kozhevnikova |
| author_sort | N. D. Vashakmadze |
| collection | DOAJ |
| description | 17 children received cardiorespiratory monitoring in order to evaluate spread and dynamics of changes in the primary obstructive sleep apnea syndrome (OSAS) parameters at type II mucopolysaccharidosis. Mild OSAS [apnea/hypopnea index (AHI) – 1.5-5] was diagnosed in 4 patients (23.5%), moderate OSAS (AHI – 5-10) – in 4 patients (23.5%), severe OSAS (AHI>10) – in 2 patients (11.8%). Average AHI at Hunter syndrome was 5.3±6.9/hour. Mild OSAS (AHI – 0.8±0.3/hour) was prevalent in the group of younger children (1-3 years of age); severe OSAS was prevalent in the group of adolescents (AHI – 10.9±9.4/hour); average blood oxygen saturation (SpO2) was 87.5±10.6%, desaturation index – 10.4±13.3/hour. In total, OSAS was observed in 58.8% of children and aggravated in direct proportion to aggravation of the disease course. Thus, cardiorespiratory monitoring is necessary to reveal children with moderate and severe OSAS course with subsequent prevention of life-threatening conditions, which may appear at this syndrome. |
| format | Article |
| id | doaj-art-220644e28d7a4aebb6c909983333d07b |
| institution | DOAJ |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2013-11-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-220644e28d7a4aebb6c909983333d07b2025-08-20T02:54:33ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892013-11-01106768110.15690/pf.v10i6.900161OBSTRUCTIVE SLEEP APNEA SYNDROME IN CHILDREN WITH TYPE II MUCOPOLYSACCHARIDOSIS (HUNTER SYNDROME)N. D. Vashakmadze0L. S. Namazova-Baranova1A. K. Gevorkyan2V. V. Altunin3L. M. Kuzenkova4E. G. Chernavina5M. A. Babaykina6T. V. Podkletnova7O. V. Kozhevnikova8Scientific Center of Children’s Health, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian Federation First Sechenov Moscow State Medical University of the Ministry of Health of the Russian Federation Pirogov Russian National Medical Research University, MoscowScientific Center of Children’s Health, Moscow, Russian Federation First Sechenov Moscow State Medical University of the Ministry of Health of the Russian FederationScientific Center of Children’s Health, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian Federation First Sechenov Moscow State Medical University of the Ministry of Health of the Russian FederationScientific Center of Children’s Health, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian Federation17 children received cardiorespiratory monitoring in order to evaluate spread and dynamics of changes in the primary obstructive sleep apnea syndrome (OSAS) parameters at type II mucopolysaccharidosis. Mild OSAS [apnea/hypopnea index (AHI) – 1.5-5] was diagnosed in 4 patients (23.5%), moderate OSAS (AHI – 5-10) – in 4 patients (23.5%), severe OSAS (AHI>10) – in 2 patients (11.8%). Average AHI at Hunter syndrome was 5.3±6.9/hour. Mild OSAS (AHI – 0.8±0.3/hour) was prevalent in the group of younger children (1-3 years of age); severe OSAS was prevalent in the group of adolescents (AHI – 10.9±9.4/hour); average blood oxygen saturation (SpO2) was 87.5±10.6%, desaturation index – 10.4±13.3/hour. In total, OSAS was observed in 58.8% of children and aggravated in direct proportion to aggravation of the disease course. Thus, cardiorespiratory monitoring is necessary to reveal children with moderate and severe OSAS course with subsequent prevention of life-threatening conditions, which may appear at this syndrome.https://www.pedpharma.ru/jour/article/view/161obstructive sleep apnea syndromehunter syndromecardiorespiratory monitoringchildren |
| spellingShingle | N. D. Vashakmadze L. S. Namazova-Baranova A. K. Gevorkyan V. V. Altunin L. M. Kuzenkova E. G. Chernavina M. A. Babaykina T. V. Podkletnova O. V. Kozhevnikova OBSTRUCTIVE SLEEP APNEA SYNDROME IN CHILDREN WITH TYPE II MUCOPOLYSACCHARIDOSIS (HUNTER SYNDROME) Педиатрическая фармакология obstructive sleep apnea syndrome hunter syndrome cardiorespiratory monitoring children |
| title | OBSTRUCTIVE SLEEP APNEA SYNDROME IN CHILDREN WITH TYPE II MUCOPOLYSACCHARIDOSIS (HUNTER SYNDROME) |
| title_full | OBSTRUCTIVE SLEEP APNEA SYNDROME IN CHILDREN WITH TYPE II MUCOPOLYSACCHARIDOSIS (HUNTER SYNDROME) |
| title_fullStr | OBSTRUCTIVE SLEEP APNEA SYNDROME IN CHILDREN WITH TYPE II MUCOPOLYSACCHARIDOSIS (HUNTER SYNDROME) |
| title_full_unstemmed | OBSTRUCTIVE SLEEP APNEA SYNDROME IN CHILDREN WITH TYPE II MUCOPOLYSACCHARIDOSIS (HUNTER SYNDROME) |
| title_short | OBSTRUCTIVE SLEEP APNEA SYNDROME IN CHILDREN WITH TYPE II MUCOPOLYSACCHARIDOSIS (HUNTER SYNDROME) |
| title_sort | obstructive sleep apnea syndrome in children with type ii mucopolysaccharidosis hunter syndrome |
| topic | obstructive sleep apnea syndrome hunter syndrome cardiorespiratory monitoring children |
| url | https://www.pedpharma.ru/jour/article/view/161 |
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