Bioactive Peptides from Sodium Caseinate Hydrolysate with High Oral Absorption Regulate Blood Glucose in Type 2 Diabetic Mice via Inhibition of DPP-IV and Stimulation of GLP-1

Bioactive Peptides from Sodium Caseinate Hydrolysate with High Oral Absorption Regulate Blood Glucose in Type 2 Diabetic Mice via Inhibition of DPP-IV and Stimulation of GLP-1

Type 2 diabetes mellitus remains a critical global health challenge, driving the pursuit of novel therapeutic strategies. This study investigated the anti-diabetic efficacy of the peptide 1CBR, derived from sodium caseinate hydrolysate, administered orally at 25 mg/kg/day to db/db mice over a 4-week...

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Bibliographic Details
Main Authors: Pei-Yu Wu, Cheng-Hong Hsieh, Ali Iqbal, Yu-Shun Lin, Ming-Wei Cheng, Ling-Hsuan Chang, Shang-Ming Huang, Kuo-Chiang Hsu
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Foods
Subjects:
type 2 diabetes mellitus
sodium caseinate hydrolysate
dipeptidyl peptidase-IV
glucagon-like peptide-1
Online Access:https://www.mdpi.com/2304-8158/14/11/1953
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