Circulating immune landscape in melanoma patients undergoing anti-PD1 therapy reveals key immune features according to clinical response to treatment

Circulating immune landscape in melanoma patients undergoing anti-PD1 therapy reveals key immune features according to clinical response to treatment

IntroductionImmune checkpoint blockers (ICB) bring unprecedented clinical success, yet many patients endure immune mediated adverse effects and/or fail to respond. Predictive signatures of response to ICB and mechanisms of clinical efficacy or failure remain understudied. DC subsets, in network with...

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Bibliographic Details
Main Authors: Eleonora Sosa Cuevas, Stéphane Mouret, Guillaume Vayssière, Siham Kerboua, Pauline Girard, Jean-Paul Molens, Marc Manceau, Julie Charles, Philippe Saas, Caroline Aspord
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
immunomonitoring
anti-PD1 therapy
melanoma
clinical response
T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1507938/full
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