The costs of urinary tract infection therapy with implementation of pharmacoeconomic guidelines at the clinic for infectious diseases of the Clinical center of Vojvodina

Beckground/Aim. The Serbian health system does not have strict guidelines for the treatment of bacterial infections. The choice of treatment is empirical which is not necessarily the same compared to the treatment guidelines from countries with a developed pharmacotherapeutic practice. In this st...

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Main Authors: Stefan-Mikić Sandra, Sević Siniša, Doder Radoslava, Cvjetković Dejan, Jovanović Nataša, Ružić Maja
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2012-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501208647S.pdf
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author Stefan-Mikić Sandra
Sević Siniša
Doder Radoslava
Cvjetković Dejan
Jovanović Nataša
Ružić Maja
author_facet Stefan-Mikić Sandra
Sević Siniša
Doder Radoslava
Cvjetković Dejan
Jovanović Nataša
Ružić Maja
author_sort Stefan-Mikić Sandra
collection DOAJ
description Beckground/Aim. The Serbian health system does not have strict guidelines for the treatment of bacterial infections. The choice of treatment is empirical which is not necessarily the same compared to the treatment guidelines from countries with a developed pharmacotherapeutic practice. In this study we compared the difference between the current treatment and the treatment taking into account the latest pharmacotherapeutic and pharmacoeconomic guidelines in order to estimate clinical efficiency of antibacterial drugs that were given as a therapy of urinary tract infections and to evaluate pharmacoeconomic aspect of this therapy as well. Methods. Our study included 100 patients that were randomly chosen and divided into 2 groups. The first group was treated in an ordinary way, while the second one was treated strictly in accordance with the guidelines (British National Formulary - BNF, and Senford Guide). In both groups of the patients we compared length of hospitalization, combination of the used antibiotics, progress as a whole in clinical picture, laboratory analyses and the price of the whole treatment. Results. Analyzing these values independently and according to statistical tests we proved that there were no significant differences between two groups with regard to the progress in a clinical picture as a whole and the length of hospitalization. According to this analysis, however suggested treatment based on guidelines showed a saving of 34.48% in comparison with the usual system of therapy. Conclusion. Efficacy of current treatment of urinary tract infection and the treatment according to foreign guidelines is the same, but the costs of the treatment are lower if the guidelines of developed health care systems are applied.
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spelling doaj-art-21f093228ec041a2ada031e2adde5cf72025-08-20T02:01:19ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502012-01-0169864765510.2298/VSP1208647SThe costs of urinary tract infection therapy with implementation of pharmacoeconomic guidelines at the clinic for infectious diseases of the Clinical center of VojvodinaStefan-Mikić SandraSević SinišaDoder RadoslavaCvjetković DejanJovanović NatašaRužić MajaBeckground/Aim. The Serbian health system does not have strict guidelines for the treatment of bacterial infections. The choice of treatment is empirical which is not necessarily the same compared to the treatment guidelines from countries with a developed pharmacotherapeutic practice. In this study we compared the difference between the current treatment and the treatment taking into account the latest pharmacotherapeutic and pharmacoeconomic guidelines in order to estimate clinical efficiency of antibacterial drugs that were given as a therapy of urinary tract infections and to evaluate pharmacoeconomic aspect of this therapy as well. Methods. Our study included 100 patients that were randomly chosen and divided into 2 groups. The first group was treated in an ordinary way, while the second one was treated strictly in accordance with the guidelines (British National Formulary - BNF, and Senford Guide). In both groups of the patients we compared length of hospitalization, combination of the used antibiotics, progress as a whole in clinical picture, laboratory analyses and the price of the whole treatment. Results. Analyzing these values independently and according to statistical tests we proved that there were no significant differences between two groups with regard to the progress in a clinical picture as a whole and the length of hospitalization. According to this analysis, however suggested treatment based on guidelines showed a saving of 34.48% in comparison with the usual system of therapy. Conclusion. Efficacy of current treatment of urinary tract infection and the treatment according to foreign guidelines is the same, but the costs of the treatment are lower if the guidelines of developed health care systems are applied.http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501208647S.pdfurinary tract infectionsantibacterial agentsdrug therapy, combinationeconomics, pharmaceuticalguidelines as topic
spellingShingle Stefan-Mikić Sandra
Sević Siniša
Doder Radoslava
Cvjetković Dejan
Jovanović Nataša
Ružić Maja
The costs of urinary tract infection therapy with implementation of pharmacoeconomic guidelines at the clinic for infectious diseases of the Clinical center of Vojvodina
Vojnosanitetski Pregled
urinary tract infections
antibacterial agents
drug therapy, combination
economics, pharmaceutical
guidelines as topic
title The costs of urinary tract infection therapy with implementation of pharmacoeconomic guidelines at the clinic for infectious diseases of the Clinical center of Vojvodina
title_full The costs of urinary tract infection therapy with implementation of pharmacoeconomic guidelines at the clinic for infectious diseases of the Clinical center of Vojvodina
title_fullStr The costs of urinary tract infection therapy with implementation of pharmacoeconomic guidelines at the clinic for infectious diseases of the Clinical center of Vojvodina
title_full_unstemmed The costs of urinary tract infection therapy with implementation of pharmacoeconomic guidelines at the clinic for infectious diseases of the Clinical center of Vojvodina
title_short The costs of urinary tract infection therapy with implementation of pharmacoeconomic guidelines at the clinic for infectious diseases of the Clinical center of Vojvodina
title_sort costs of urinary tract infection therapy with implementation of pharmacoeconomic guidelines at the clinic for infectious diseases of the clinical center of vojvodina
topic urinary tract infections
antibacterial agents
drug therapy, combination
economics, pharmaceutical
guidelines as topic
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501208647S.pdf
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