Lacticaseibacillus casei IDCC 3451 alleviates cognitive and behavioral functions by reshaping the gut microbiome and regulating intestinal barrier integrity in chronic stress animal models

Lacticaseibacillus casei IDCC 3451 alleviates cognitive and behavioral functions by reshaping the gut microbiome and regulating intestinal barrier integrity in chronic stress animal models

Lacticaseibacillus casei IDCC 3451 (3451) was evaluated for its effects on the gut-brain axis using Caenorhabditis elegans (C. elegans) and mouse models of stress and inflammation. In C. elegans, 3451 extended lifespans by 25 %, improved motility, and chemotaxis, enhanced survival under pathogen cha...

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Bibliographic Details
Main Authors: Anna Kang, Ju Young Eor, Junbeom Lee, Min-Jin Kwak, Daniel Junpyo Lee, Eunsol Seo, Woong Ji Lee, Seon-hui Son, Minho Song, Jun-Mo Kim, Hyung Wook Kim, Jungwoo Yang, Sangnam Oh, Younghoon Kim
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Food Science
Subjects:
C. elegans
L. casei
Probiotics
Gut–brain axis
Chronic stress
DSS-Induced colitis
Online Access:http://www.sciencedirect.com/science/article/pii/S2665927125000826
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