Distinct 5-methylcytosine profiles of LncRNA in breast cancer brain metastasis

Distinct 5-methylcytosine profiles of LncRNA in breast cancer brain metastasis

Abstract Background Recent studies have identified a complex relationship between methylation patterns and the development of various cancers. Breast cancer (BC) is the second leading cause of cancer mortality among women. Approximately 5–20% of BC patients are at risk of BC brain metastases (BCBM)....

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Bibliographic Details
Main Authors: Song Wang, Jianran Guo, Xinmiao Xian, Min Li, Anqi Zhang, Yujiao Liu, Yifei Zhang, Shen Chen, Guohao Gu, Xuehua Zhang, Dong Yan, Meng An, Li Pan, Bo Fu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Cancer
Subjects:
Breast Cancer Brain Metastases (BCBM)
5-methylcytosine (m5C)
Long non-coding RNA (lncRNA)
Methylated RNA Immunoprecipitation next-generation sequencing (MeRIP-seq)
Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG)
Methylation regulators
Online Access:https://doi.org/10.1186/s12885-025-13948-w
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