Acute high-intensity noise exposure exacerbates anxiety-like behavior via neuroinflammation and blood brain barrier disruption of hippocampus in male rats

Acute high-intensity noise exposure exacerbates anxiety-like behavior via neuroinflammation and blood brain barrier disruption of hippocampus in male rats

Abstract The health risks associated with acute noise exposure are increasing, particularly the risk of mental health. This study aims to identify the association between acute high-intensity noise exposure and anxiety behavior in male rats, and to explore the associated neurobiological mechanisms....

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Bibliographic Details
Main Authors: Yifei Song, Haoyu Zhang, Xiaoni Wang, Lei Huang, Yiting Kang, Zeguo Feng, Fadong Zhao, Hongwei Zhuang, Jianbao Zhang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Behavioral and Brain Functions
Subjects:
Acute noise
Anxiety
Hippocampus
Neuroinflammation
Blood brain barrier
Online Access:https://doi.org/10.1186/s12993-025-00275-0
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