Head and neck tumor organoid grown under simplified media conditions model tumor biology and chemoradiation responses

Head and neck tumor organoid grown under simplified media conditions model tumor biology and chemoradiation responses

Abstract Head and neck squamous cell carcinoma (HNSCC) is a prevalent and often fatal malignancy associated with significant treatment-related toxicity. There is an urgent need for a preclinical model to assess therapeutic options and guide clinical decision-making. To define conditions for establis...

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Main Authors: Weilin Li, Michiya Nishino, Eric Reed, Dipikaa Akshinthala, Hamdan Ahmed Pasha, Erik S. Anderson, Ling Huang, Hannah Hebestreit, Stefano Monti, Ernest D. Gomez, Scharukh M. Jalisi, Senthil K. Muthuswamy
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-88082-5
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