Granulation Methods and the Mechanisms for Improving Hardness of Loxoprofen Sodium Hydrate-Containing Tablets

<b>Objectives:</b> We investigated the compression mechanisms for loxoprofen sodium (LXP), which is known to occur as a dihydrate, and identified parameters that influence the tablet hardness of LXP tablets prepared by the wet granulation method. <b>Method:</b> LXP granules w...

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Bibliographic Details
Main Authors: Aya Kuwata, Agata Ishikawa, Tetsuo Ono, Etsuo Yonemochi
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceutics
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Online Access:https://www.mdpi.com/1999-4923/17/4/455
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