Cryo-EM structure of the Mycobacterium smegmatis MmpL5-AcpM complex

Cryo-EM structure of the Mycobacterium smegmatis MmpL5-AcpM complex

ABSTRACT Mycobacterium tuberculosis, the causative agent of the airborne infection tuberculosis (TB), contains 13 mycobacterial membrane protein large (MmpL) transporters that can be divided into two distinct subclasses. These MmpL proteins play important functional roles within the mycobacterium an...

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Bibliographic Details
Main Authors: Rakesh Maharjan, Zhemin Zhang, Philip A. Klenotic, William D. Gregor, Georgiana E. Purdy, Edward W. Yu
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mBio
Subjects:
Mycobacterial membrane protein Large
MmpL5
acyl carrier protein M
mycobactin L
siderophore export
iron acquisition
Online Access:https://journals.asm.org/doi/10.1128/mbio.03035-24
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