Evaluation of low gradient severe aortic stenosis: should we change our outlook in the analysis of clinical data?

Nowadays, technological progress has equipped clinicians with new useful devices for the collection, analysis and presentation of data. As a consequence, many diseases and pathological conditions have been studied in a more detailed way, sometimes with remarkable results. In fact, they are not alway...

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Main Authors: Ivan Corazza, Margherita Zecchi, Romano Zannoli
Format: Article
Language:English
Published: BMJ Publishing Group 2021-12-01
Series:Open Heart
Online Access:https://openheart.bmj.com/content/8/2/e001746.full
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author Ivan Corazza
Margherita Zecchi
Romano Zannoli
author_facet Ivan Corazza
Margherita Zecchi
Romano Zannoli
author_sort Ivan Corazza
collection DOAJ
description Nowadays, technological progress has equipped clinicians with new useful devices for the collection, analysis and presentation of data. As a consequence, many diseases and pathological conditions have been studied in a more detailed way, sometimes with remarkable results. In fact, they are not always validated by the old physiological models. In this respect, we present the case of low gradient severe aortic stenosis, a condition characterised by a small aortic valve area and a low-pressure gradient. According to the mathematical and physical assumptions these readings are contradictory whereas the Doppler-echocardiography shows clearly the existence of such a situation. In this work, we have described the physiological base of this phenomenon and discussed the limitations of the technology used. In this work, we are going to analyse some conditions commonly observed in daily clinical practice in order to prompt a critical outlook in both clinicians and technicians about the instrumentations used and the methods applied.
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series Open Heart
spelling doaj-art-21c34485cf2d4e17a0348f2f90ec01462025-08-20T02:13:52ZengBMJ Publishing GroupOpen Heart2053-36242021-12-018210.1136/openhrt-2021-001746Evaluation of low gradient severe aortic stenosis: should we change our outlook in the analysis of clinical data?Ivan Corazza0Margherita Zecchi1Romano Zannoli2Department of Experimental Diagnostic and Specialty Medicine, Alma Mater Studiorum University of Bologna, Bologna, ItalyDepartment of Experimental Diagnostic and Specialty Medicine, Alma Mater Studiorum University of Bologna, Bologna, ItalyDepartment of Experimental Diagnostic and Specialty Medicine, Alma Mater Studiorum University of Bologna, Bologna, ItalyNowadays, technological progress has equipped clinicians with new useful devices for the collection, analysis and presentation of data. As a consequence, many diseases and pathological conditions have been studied in a more detailed way, sometimes with remarkable results. In fact, they are not always validated by the old physiological models. In this respect, we present the case of low gradient severe aortic stenosis, a condition characterised by a small aortic valve area and a low-pressure gradient. According to the mathematical and physical assumptions these readings are contradictory whereas the Doppler-echocardiography shows clearly the existence of such a situation. In this work, we have described the physiological base of this phenomenon and discussed the limitations of the technology used. In this work, we are going to analyse some conditions commonly observed in daily clinical practice in order to prompt a critical outlook in both clinicians and technicians about the instrumentations used and the methods applied.https://openheart.bmj.com/content/8/2/e001746.full
spellingShingle Ivan Corazza
Margherita Zecchi
Romano Zannoli
Evaluation of low gradient severe aortic stenosis: should we change our outlook in the analysis of clinical data?
Open Heart
title Evaluation of low gradient severe aortic stenosis: should we change our outlook in the analysis of clinical data?
title_full Evaluation of low gradient severe aortic stenosis: should we change our outlook in the analysis of clinical data?
title_fullStr Evaluation of low gradient severe aortic stenosis: should we change our outlook in the analysis of clinical data?
title_full_unstemmed Evaluation of low gradient severe aortic stenosis: should we change our outlook in the analysis of clinical data?
title_short Evaluation of low gradient severe aortic stenosis: should we change our outlook in the analysis of clinical data?
title_sort evaluation of low gradient severe aortic stenosis should we change our outlook in the analysis of clinical data
url https://openheart.bmj.com/content/8/2/e001746.full
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AT romanozannoli evaluationoflowgradientsevereaorticstenosisshouldwechangeouroutlookintheanalysisofclinicaldata