Molecular features of TNBC govern heterogeneity in the response to radiation and autophagy inhibition

Molecular features of TNBC govern heterogeneity in the response to radiation and autophagy inhibition

Abstract Triple negative breast cancer (TNBC) is a heterogeneous and a highly aggressive type of breast cancer. Standard of care for TNBC patients includes surgery, radio-, chemo- and immunotherapy, depending on the stage of the disease. Immunotherapy is ineffective as monotherapy but can be enhance...

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Main Authors: Patrick Fischer, Maximilian Schmid, Anna Ohradanova-Repic, Rebecca Schneeweiss, Jana Hadatsch, Odysseus Grünert, Johannes Benedum, Anna Röhrer, Felix Staudinger, Philipp Schatzlmaier, Niccolo Bragato, Sandra Barna, Magdalena Engl, Ava Kleinwächter, Dietmar Georg, Joachim Widder, Sylvia Kerschbaum-Gruber, Dea Slade
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07873-w
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