Impact of aminoglycosides on survival rate and renal outcomes in patients with urosepsis: a multicenter retrospective study

Impact of aminoglycosides on survival rate and renal outcomes in patients with urosepsis: a multicenter retrospective study

Abstract Background Combination therapy with a beta-lactam and an aminoglycoside is currently recommended for the empirical treatment of urosepsis. Nephrotoxicity is the most common adverse effect of aminoglycosides and acute kidney injury (AKI) has a significant prognostic impact in septic shock. T...

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Bibliographic Details
Main Authors: David Rozenblat, Arnaud Serret-Larmande, Alexis Maillard, Romain Arrestier, Sarah Benghanem, Julien Charpentier, Michael Darmon, Vincent Das, François Dépret, Jean Luc Donay, Hervé Jacquier, Hélène Poupet, Jean-Michel Molina, Matthieu Lafaurie
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Annals of Intensive Care
Subjects:
Urinary tract infections
Septic shock
Aminoglycosides
Acute kidney injury
Mortality
Online Access:https://doi.org/10.1186/s13613-025-01469-5
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