Hypothesized pharmacogenomic and medication influences on tetrahydrocannabinol and cannabidiol metabolism in a cohort of unselected oral cannabis users

Hypothesized pharmacogenomic and medication influences on tetrahydrocannabinol and cannabidiol metabolism in a cohort of unselected oral cannabis users

Abstract Background Differences in cannabinoid metabolism and patient responses can arise even with equivalent doses and formulations. Genetic polymorphisms in genes responsible for cannabinoid metabolism and medications that alter CYP450 pathways responsible for metabolism of cannabinoids may accou...

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Bibliographic Details
Main Authors: Jessica A. Wright, Linda Huang, Basant E. Katamesh, Siddhant Yadav, Abhinav Singla, Ann Vincent
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Cannabis Research
Subjects:
Pharmacogenomics
Potential drug-gene interactions
CBD
THC
CYP450 enzyme
Pharmacology
Online Access:https://doi.org/10.1186/s42238-024-00256-6
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