Effectiveness of web-based interventions for women with urinary incontinence: protocol for a systematic review and meta-analysis of randomised controlled trials

Introduction Urinary incontinence (UI) is one of the most common chronic diseases among women, which can endanger their physical and mental health and incur a heavy financial burden on both individuals and society. Web-based interventions (WBIs) have been applied to manage women’s UI, but their effe...

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Main Authors: Hongyan Wang, Ping Xu, Wei Zhang, Ying Jin, Xiaojuan Wang, Dan Dan Chen, Weijing Chen, Pingping Guo, Minna Mao, Suwen Feng, Rujia Zhao, Xuefen Xu, Fang Xie
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/3/e081731.full
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author Hongyan Wang
Ping Xu
Wei Zhang
Ying Jin
Xiaojuan Wang
Dan Dan Chen
Weijing Chen
Pingping Guo
Minna Mao
Suwen Feng
Rujia Zhao
Xuefen Xu
Fang Xie
author_facet Hongyan Wang
Ping Xu
Wei Zhang
Ying Jin
Xiaojuan Wang
Dan Dan Chen
Weijing Chen
Pingping Guo
Minna Mao
Suwen Feng
Rujia Zhao
Xuefen Xu
Fang Xie
author_sort Hongyan Wang
collection DOAJ
description Introduction Urinary incontinence (UI) is one of the most common chronic diseases among women, which can endanger their physical and mental health and incur a heavy financial burden on both individuals and society. Web-based interventions (WBIs) have been applied to manage women’s UI, but their effectiveness has remained inconclusive. This systematic review and meta-analysis aims to explore the effectiveness of WBIs on self-reported symptom severity, condition-specific quality of life, adherence to pelvic floor muscle training (primary outcomes) and other extensive secondary outcomes among women with UI. We also aimed to investigate whether intervention characteristics (format, interactivity and main technology) have impacts on the effectiveness of primary outcomes.Methods and analysis This systematic review protocol was developed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guidelines. 10 electronic databases will be comprehensively searched from their inception to 1 May 2024, along with grey literature searches and manual reviews of relevant reference lists to identify eligible randomised controlled trials. The methodological quality of the included studies will be assessed by two reviewers based on the Cochrane Risk of Bias Tool. Meta-analyses will be conducted via Stata V.12.0. Leave-one-out sensitivity analyses will be performed, and publication bias will be evaluated using funnel plots and Egger’s test. Subgroup analyses regarding intervention format, interactivity and main technology will be carried out.Ethics and dissemination No ethics approval is needed for this review since no primary data are to be collected. The results of this review will help develop an optimal WBI for women with UI, thereby providing them with maximum benefits. The findings will be disseminated via a peer-reviewed journal or conference presentation.PROSPERO registration number CRD42023435047.
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spelling doaj-art-21bad1f5a5ea4309b87d699b70a40df02025-08-20T03:12:46ZengBMJ Publishing GroupBMJ Open2044-60552024-03-0114310.1136/bmjopen-2023-081731Effectiveness of web-based interventions for women with urinary incontinence: protocol for a systematic review and meta-analysis of randomised controlled trialsHongyan Wang0Ping Xu1Wei Zhang2Ying Jin3Xiaojuan Wang4Dan Dan Chen5Weijing Chen6Pingping Guo7Minna Mao8Suwen Feng9Rujia Zhao10Xuefen Xu11Fang Xie12Women`s Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang, ChinaWomen’s Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaWomen`s Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang, China1Tavotek Biotherapeutics, Suzhou, Jiangsu, ChinaWomen’s Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaFaculty of Nursing, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Obstetrics, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaWomen`s Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang, ChinaWomen`s Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang, ChinaWomen`s Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang, ChinaWomen`s Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang, ChinaWomen`s Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang, ChinaWomen`s Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang, ChinaIntroduction Urinary incontinence (UI) is one of the most common chronic diseases among women, which can endanger their physical and mental health and incur a heavy financial burden on both individuals and society. Web-based interventions (WBIs) have been applied to manage women’s UI, but their effectiveness has remained inconclusive. This systematic review and meta-analysis aims to explore the effectiveness of WBIs on self-reported symptom severity, condition-specific quality of life, adherence to pelvic floor muscle training (primary outcomes) and other extensive secondary outcomes among women with UI. We also aimed to investigate whether intervention characteristics (format, interactivity and main technology) have impacts on the effectiveness of primary outcomes.Methods and analysis This systematic review protocol was developed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guidelines. 10 electronic databases will be comprehensively searched from their inception to 1 May 2024, along with grey literature searches and manual reviews of relevant reference lists to identify eligible randomised controlled trials. The methodological quality of the included studies will be assessed by two reviewers based on the Cochrane Risk of Bias Tool. Meta-analyses will be conducted via Stata V.12.0. Leave-one-out sensitivity analyses will be performed, and publication bias will be evaluated using funnel plots and Egger’s test. Subgroup analyses regarding intervention format, interactivity and main technology will be carried out.Ethics and dissemination No ethics approval is needed for this review since no primary data are to be collected. The results of this review will help develop an optimal WBI for women with UI, thereby providing them with maximum benefits. The findings will be disseminated via a peer-reviewed journal or conference presentation.PROSPERO registration number CRD42023435047.https://bmjopen.bmj.com/content/14/3/e081731.full
spellingShingle Hongyan Wang
Ping Xu
Wei Zhang
Ying Jin
Xiaojuan Wang
Dan Dan Chen
Weijing Chen
Pingping Guo
Minna Mao
Suwen Feng
Rujia Zhao
Xuefen Xu
Fang Xie
Effectiveness of web-based interventions for women with urinary incontinence: protocol for a systematic review and meta-analysis of randomised controlled trials
BMJ Open
title Effectiveness of web-based interventions for women with urinary incontinence: protocol for a systematic review and meta-analysis of randomised controlled trials
title_full Effectiveness of web-based interventions for women with urinary incontinence: protocol for a systematic review and meta-analysis of randomised controlled trials
title_fullStr Effectiveness of web-based interventions for women with urinary incontinence: protocol for a systematic review and meta-analysis of randomised controlled trials
title_full_unstemmed Effectiveness of web-based interventions for women with urinary incontinence: protocol for a systematic review and meta-analysis of randomised controlled trials
title_short Effectiveness of web-based interventions for women with urinary incontinence: protocol for a systematic review and meta-analysis of randomised controlled trials
title_sort effectiveness of web based interventions for women with urinary incontinence protocol for a systematic review and meta analysis of randomised controlled trials
url https://bmjopen.bmj.com/content/14/3/e081731.full
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