Platelet Activation on Lung Function During Ex Vivo Lung Perfusion, Lung Transplantation, and the Role of Antiplatelet Therapy: A Narrative Review

Background. Ischemia/reperfusion injury after lung transplantation is a significant cause of morbidity. In the realm of ex vivo lung perfusion (EVLP), inflammation, edema formation, and reduced compliance have limited the durability of EVLP. Previous evidence has suggested that platelet activation a...

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Main Authors: Ryaan EL-Andari, MD, Jimmy J.H. Kang, MD, Nicholas M. Fialka, MD, Jason Weatherald, MD, Parnian Alavi, MSc, Nadia Jahroudi, PhD, Darren H. Freed, MD, PhD, Jayan Nagendran, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2025-09-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001855
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