Does Early Decompressive Craniectomy Improve Outcome? Experience from an Active UK Recruiter Centre

Introduction. The results of the recent DECRA study suggest that although craniectomy decreases ICP and ICU length of stay, it is also associated with worst outcomes. Our experience, illustrated by these two striking cases, supports that early decompressive craniectomy may significantly improve the...

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Main Authors: E. García Vicente, V. Garnelo Rey, M. Manikon, S. Ashworth, M. H. Wilson
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2013/714945
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author E. García Vicente
V. Garnelo Rey
M. Manikon
S. Ashworth
M. H. Wilson
author_facet E. García Vicente
V. Garnelo Rey
M. Manikon
S. Ashworth
M. H. Wilson
author_sort E. García Vicente
collection DOAJ
description Introduction. The results of the recent DECRA study suggest that although craniectomy decreases ICP and ICU length of stay, it is also associated with worst outcomes. Our experience, illustrated by these two striking cases, supports that early decompressive craniectomy may significantly improve the outcome in selected patients. Case Reports. The first patient, a 20-year-old man who suffered severe brain contusion and subarachnoid haemorrhage after a fall downstairs, with refractory ICP of 35 mmHg, despite maximal medical therapy, eventually underwent decompressive craniectomy. After 18 days in intensive care, he was discharged for rehabilitation. The second patient, a 23-year-old man was found at the scene of a road accident with a GCS of 3 and fixed, dilated pupils who underwent extensive unilateral decompressive craniectomy for refractory intracranial hypertension. After three weeks of cooling, paralysis, and neuroprotection, he eventually left ICU for rehabilitation. Outcomes. Four months after leaving ICU, the first patient abseiled 40 m down the main building of St. Mary’s Hospital to raise money for the Trauma Unit. He has returned to part-time work. The second patient, was decannulated less than a month later and made a full cognitive recovery. A year later, with a titanium skull prosthesis, he is back to part-time work and to playing football. Conclusions. Despite the conclusions of the DECRA study, our experience of the use of early decompressive craniectomy has been associated with outstanding outcomes. We are currently actively recruiting patients into the RESCUEicp trial and have high hopes that it will clarify the role of the decompressive craniectomy in traumatic brain injury and whether it effectively improves outcomes.
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spelling doaj-art-21b345ccf1a0426f8fc2fd36e3e2583c2025-08-20T03:54:42ZengWileyCase Reports in Critical Care2090-64202090-64392013-01-01201310.1155/2013/714945714945Does Early Decompressive Craniectomy Improve Outcome? Experience from an Active UK Recruiter CentreE. García Vicente0V. Garnelo Rey1M. Manikon2S. Ashworth3M. H. Wilson4Adult Intensive Care Unit, St. Mary's Hospital, Imperial College NHS Trust, London W2 6HP, UKAdult Intensive Care Unit, St. Mary's Hospital, Imperial College NHS Trust, London W2 6HP, UKAdult Intensive Care Unit, St. Mary's Hospital, Imperial College NHS Trust, London W2 6HP, UKAdult Intensive Care Unit, St. Mary's Hospital, Imperial College NHS Trust, London W2 6HP, UKNeurosurgery Department, St. Mary's Hospital, Imperial College NHS Trust, London W2 6HP, UKIntroduction. The results of the recent DECRA study suggest that although craniectomy decreases ICP and ICU length of stay, it is also associated with worst outcomes. Our experience, illustrated by these two striking cases, supports that early decompressive craniectomy may significantly improve the outcome in selected patients. Case Reports. The first patient, a 20-year-old man who suffered severe brain contusion and subarachnoid haemorrhage after a fall downstairs, with refractory ICP of 35 mmHg, despite maximal medical therapy, eventually underwent decompressive craniectomy. After 18 days in intensive care, he was discharged for rehabilitation. The second patient, a 23-year-old man was found at the scene of a road accident with a GCS of 3 and fixed, dilated pupils who underwent extensive unilateral decompressive craniectomy for refractory intracranial hypertension. After three weeks of cooling, paralysis, and neuroprotection, he eventually left ICU for rehabilitation. Outcomes. Four months after leaving ICU, the first patient abseiled 40 m down the main building of St. Mary’s Hospital to raise money for the Trauma Unit. He has returned to part-time work. The second patient, was decannulated less than a month later and made a full cognitive recovery. A year later, with a titanium skull prosthesis, he is back to part-time work and to playing football. Conclusions. Despite the conclusions of the DECRA study, our experience of the use of early decompressive craniectomy has been associated with outstanding outcomes. We are currently actively recruiting patients into the RESCUEicp trial and have high hopes that it will clarify the role of the decompressive craniectomy in traumatic brain injury and whether it effectively improves outcomes.http://dx.doi.org/10.1155/2013/714945
spellingShingle E. García Vicente
V. Garnelo Rey
M. Manikon
S. Ashworth
M. H. Wilson
Does Early Decompressive Craniectomy Improve Outcome? Experience from an Active UK Recruiter Centre
Case Reports in Critical Care
title Does Early Decompressive Craniectomy Improve Outcome? Experience from an Active UK Recruiter Centre
title_full Does Early Decompressive Craniectomy Improve Outcome? Experience from an Active UK Recruiter Centre
title_fullStr Does Early Decompressive Craniectomy Improve Outcome? Experience from an Active UK Recruiter Centre
title_full_unstemmed Does Early Decompressive Craniectomy Improve Outcome? Experience from an Active UK Recruiter Centre
title_short Does Early Decompressive Craniectomy Improve Outcome? Experience from an Active UK Recruiter Centre
title_sort does early decompressive craniectomy improve outcome experience from an active uk recruiter centre
url http://dx.doi.org/10.1155/2013/714945
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