Care and treatment for primary cutaneous lymphoma-associated ulcers: Two case reports

Primary cutaneous lymphoma is a heterogeneous group of cutaneous lymphocytic primary tumors belonging to the extranodal category of non-Hodgkin lymphoma. Skin is the second most common site of extranodal non-Hodgkin lymphoma after the gastrointestinal tract. Skin lesions are the main manifestations...

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Main Authors: Min Wei, Jun Wei, Jian Li, Ruyue Li, Jing Liu
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X251353597
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author Min Wei
Jun Wei
Jian Li
Ruyue Li
Jing Liu
author_facet Min Wei
Jun Wei
Jian Li
Ruyue Li
Jing Liu
author_sort Min Wei
collection DOAJ
description Primary cutaneous lymphoma is a heterogeneous group of cutaneous lymphocytic primary tumors belonging to the extranodal category of non-Hodgkin lymphoma. Skin is the second most common site of extranodal non-Hodgkin lymphoma after the gastrointestinal tract. Skin lesions are the main manifestations of primary cutaneous lymphoma. Here, we report two successful cases of skin ulcers caused by primary cutaneous lymphoma, which is both rare and difficult to diagnose. One case involved primary cutaneous T-cell lymphoma, and the other involved primary cutaneous B-cell lymphoma. Systemic antitumor therapy combined with the right local wound management is the key to ulcer healing. For wound management, in addition to infection control, exudate management, pain control, and odor management, evaluation and intervention of debridement are worthy of consideration, but they must be evaluated by an expert group, and plans must be made for bleeding. Finally, the wounds of the two patients were completely healed after 79 and 65 days under active systemic therapy.
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institution Kabale University
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spelling doaj-art-21aba26f5d2e4d61be2dd70e9c1b87412025-08-20T03:26:43ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-06-011310.1177/2050313X251353597Care and treatment for primary cutaneous lymphoma-associated ulcers: Two case reportsMin Wei0Jun Wei1Jian Li2Ruyue Li3Jing Liu4Wound Care Center, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Jiangsu, ChinaDepartment of Medical Records and Statistics, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, Jiangsu, ChinaWound Care Center, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Jiangsu, ChinaWound Care Center, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Jiangsu, ChinaChina Hospital Reform and Development Research Institute of Nanjing University, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Jiangsu, ChinaPrimary cutaneous lymphoma is a heterogeneous group of cutaneous lymphocytic primary tumors belonging to the extranodal category of non-Hodgkin lymphoma. Skin is the second most common site of extranodal non-Hodgkin lymphoma after the gastrointestinal tract. Skin lesions are the main manifestations of primary cutaneous lymphoma. Here, we report two successful cases of skin ulcers caused by primary cutaneous lymphoma, which is both rare and difficult to diagnose. One case involved primary cutaneous T-cell lymphoma, and the other involved primary cutaneous B-cell lymphoma. Systemic antitumor therapy combined with the right local wound management is the key to ulcer healing. For wound management, in addition to infection control, exudate management, pain control, and odor management, evaluation and intervention of debridement are worthy of consideration, but they must be evaluated by an expert group, and plans must be made for bleeding. Finally, the wounds of the two patients were completely healed after 79 and 65 days under active systemic therapy.https://doi.org/10.1177/2050313X251353597
spellingShingle Min Wei
Jun Wei
Jian Li
Ruyue Li
Jing Liu
Care and treatment for primary cutaneous lymphoma-associated ulcers: Two case reports
SAGE Open Medical Case Reports
title Care and treatment for primary cutaneous lymphoma-associated ulcers: Two case reports
title_full Care and treatment for primary cutaneous lymphoma-associated ulcers: Two case reports
title_fullStr Care and treatment for primary cutaneous lymphoma-associated ulcers: Two case reports
title_full_unstemmed Care and treatment for primary cutaneous lymphoma-associated ulcers: Two case reports
title_short Care and treatment for primary cutaneous lymphoma-associated ulcers: Two case reports
title_sort care and treatment for primary cutaneous lymphoma associated ulcers two case reports
url https://doi.org/10.1177/2050313X251353597
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