Myocardial and Microvascular Injury Due to Coronavirus Disease 2019
Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respirato...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Radcliffe Medical Media
2020-06-01
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| Series: | European Cardiology Review |
| Online Access: | https://www.ecrjournal.com/articleindex/ecr.2020.22 |
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| _version_ | 1850256256131923968 |
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| author | Rocco A Montone Giulia Iannaccone Maria Chiara Meucci Filippo Gurgoglione Giampaolo Niccoli |
| author_facet | Rocco A Montone Giulia Iannaccone Maria Chiara Meucci Filippo Gurgoglione Giampaolo Niccoli |
| author_sort | Rocco A Montone |
| collection | DOAJ |
| description | Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications. |
| format | Article |
| id | doaj-art-21ab3b263d704cb68eb18440257533f9 |
| institution | OA Journals |
| issn | 1758-3756 1758-3764 |
| language | English |
| publishDate | 2020-06-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | European Cardiology Review |
| spelling | doaj-art-21ab3b263d704cb68eb18440257533f92025-08-20T01:56:41ZengRadcliffe Medical MediaEuropean Cardiology Review1758-37561758-37642020-06-011510.15420/ecr.2020.22Myocardial and Microvascular Injury Due to Coronavirus Disease 2019Rocco A Montone0Giulia Iannaccone1Maria Chiara Meucci2Filippo Gurgoglione3Giampaolo Niccoli4Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, ItalyDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, ItalyDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, ItalyDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, ItalyDepartment of Cardiovascular Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy; Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, ItalyOver the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications.https://www.ecrjournal.com/articleindex/ecr.2020.22 |
| spellingShingle | Rocco A Montone Giulia Iannaccone Maria Chiara Meucci Filippo Gurgoglione Giampaolo Niccoli Myocardial and Microvascular Injury Due to Coronavirus Disease 2019 European Cardiology Review |
| title | Myocardial and Microvascular Injury Due to Coronavirus Disease 2019 |
| title_full | Myocardial and Microvascular Injury Due to Coronavirus Disease 2019 |
| title_fullStr | Myocardial and Microvascular Injury Due to Coronavirus Disease 2019 |
| title_full_unstemmed | Myocardial and Microvascular Injury Due to Coronavirus Disease 2019 |
| title_short | Myocardial and Microvascular Injury Due to Coronavirus Disease 2019 |
| title_sort | myocardial and microvascular injury due to coronavirus disease 2019 |
| url | https://www.ecrjournal.com/articleindex/ecr.2020.22 |
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