Myocardial and Microvascular Injury Due to Coronavirus Disease 2019

Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respirato...

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Bibliographic Details
Main Authors: Rocco A Montone, Giulia Iannaccone, Maria Chiara Meucci, Filippo Gurgoglione, Giampaolo Niccoli
Format: Article
Language:English
Published: Radcliffe Medical Media 2020-06-01
Series:European Cardiology Review
Online Access:https://www.ecrjournal.com/articleindex/ecr.2020.22
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Summary:Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications.
ISSN:1758-3756
1758-3764