Adult-onset Renal Neuroblastoma: Case Report and Literature Review

Neuroblastoma is an extremely rare neoplasm in adults, with a poorer prognosis compared to pediatric neuroblastoma. Due to its rarity, there are no specific treatment guidelines for adult neuroblastoma. Here, we report a case of adult renal neuroblastoma presenting initially with painless and gross...

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Main Authors: Yao-Ren Yang, Cih-En Huang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Cancer Research and Practice
Subjects:
Online Access:https://journals.lww.com/10.4103/ejcrp.eJCRP-D-24-00017
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author Yao-Ren Yang
Cih-En Huang
author_facet Yao-Ren Yang
Cih-En Huang
author_sort Yao-Ren Yang
collection DOAJ
description Neuroblastoma is an extremely rare neoplasm in adults, with a poorer prognosis compared to pediatric neuroblastoma. Due to its rarity, there are no specific treatment guidelines for adult neuroblastoma. Here, we report a case of adult renal neuroblastoma presenting initially with painless and gross hematuria. Enhanced computed tomography revealed an infiltrative, heterogeneously enhanced renal mass at the lower pole of the right kidney, accompanied by regional lymphadenopathies. The initial impression was renal cell carcinoma, and a right nephroureterectomy with regional lymph node dissection was performed. Pathologic examination confirmed the diagnosis of primary renal neuroblastoma with a differentiating subtype. The patient was classified as having International Neuroblastoma Staging System stage 2B or International Neuroblastoma Risk Group Staging System stage L2. The patient underwent six courses of adjuvant chemotherapy, and no disease recurrence was observed during a 7-year follow-up period.
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institution Kabale University
issn 2311-3006
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publisher Wolters Kluwer Medknow Publications
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series Journal of Cancer Research and Practice
spelling doaj-art-219dc0687d8646408f4b24c6236dbbf52025-01-10T12:26:49ZengWolters Kluwer Medknow PublicationsJournal of Cancer Research and Practice2311-30062024-12-0111415515810.4103/ejcrp.eJCRP-D-24-00017Adult-onset Renal Neuroblastoma: Case Report and Literature ReviewYao-Ren YangCih-En HuangNeuroblastoma is an extremely rare neoplasm in adults, with a poorer prognosis compared to pediatric neuroblastoma. Due to its rarity, there are no specific treatment guidelines for adult neuroblastoma. Here, we report a case of adult renal neuroblastoma presenting initially with painless and gross hematuria. Enhanced computed tomography revealed an infiltrative, heterogeneously enhanced renal mass at the lower pole of the right kidney, accompanied by regional lymphadenopathies. The initial impression was renal cell carcinoma, and a right nephroureterectomy with regional lymph node dissection was performed. Pathologic examination confirmed the diagnosis of primary renal neuroblastoma with a differentiating subtype. The patient was classified as having International Neuroblastoma Staging System stage 2B or International Neuroblastoma Risk Group Staging System stage L2. The patient underwent six courses of adjuvant chemotherapy, and no disease recurrence was observed during a 7-year follow-up period.https://journals.lww.com/10.4103/ejcrp.eJCRP-D-24-00017adultchemotherapykidneynephrectomyneuroblastoma
spellingShingle Yao-Ren Yang
Cih-En Huang
Adult-onset Renal Neuroblastoma: Case Report and Literature Review
Journal of Cancer Research and Practice
adult
chemotherapy
kidney
nephrectomy
neuroblastoma
title Adult-onset Renal Neuroblastoma: Case Report and Literature Review
title_full Adult-onset Renal Neuroblastoma: Case Report and Literature Review
title_fullStr Adult-onset Renal Neuroblastoma: Case Report and Literature Review
title_full_unstemmed Adult-onset Renal Neuroblastoma: Case Report and Literature Review
title_short Adult-onset Renal Neuroblastoma: Case Report and Literature Review
title_sort adult onset renal neuroblastoma case report and literature review
topic adult
chemotherapy
kidney
nephrectomy
neuroblastoma
url https://journals.lww.com/10.4103/ejcrp.eJCRP-D-24-00017
work_keys_str_mv AT yaorenyang adultonsetrenalneuroblastomacasereportandliteraturereview
AT cihenhuang adultonsetrenalneuroblastomacasereportandliteraturereview