APJ regulates the balance between self-renewal and differentiation of vascular endothelial stem cells

APJ regulates the balance between self-renewal and differentiation of vascular endothelial stem cells

Abstract Background CD157 marks a population of tissue-resident vascular endothelial stem cells (VESCs) in mice known for their critical role in homeostatic endothelial cell (EC) turnover and the rapid response to vascular damage in the liver by regeneration. Nevertheless, the mechanism underlying t...

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Bibliographic Details
Main Authors: Man Wang, Fitriana Nur Rahmawati, Wenting Li, Zeynep Bal, Faya Nuralda Sitompul, Fumitaka Muramatsu, Weizhen Jia, Nobuyuki Takakura
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Inflammation and Regeneration
Subjects:
Endothelial cells
Endothelial cell differentiation
Endothelial stem cells
Vascular repair
Online Access:https://doi.org/10.1186/s41232-025-00389-y
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https://doi.org/10.1186/s41232-025-00389-y

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