Associations between oxidative balance scores and heart failure among americans: NHANES (2007–2018)
Abstract Background The relationship between oxidative balance score (OBS) and heart failure (HF) is controversial. The OBS was used to assess systemic oxidative stress status, with higher OBS scores implying exposure to more antioxidants. This study aimed to explore whether OBS is associated with h...
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BMC
2025-01-01
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| Series: | BMC Cardiovascular Disorders |
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| Online Access: | https://doi.org/10.1186/s12872-024-04456-z |
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| author | Xiaozhuo Xu Xueli Wang Xu Han |
| author_facet | Xiaozhuo Xu Xueli Wang Xu Han |
| author_sort | Xiaozhuo Xu |
| collection | DOAJ |
| description | Abstract Background The relationship between oxidative balance score (OBS) and heart failure (HF) is controversial. The OBS was used to assess systemic oxidative stress status, with higher OBS scores implying exposure to more antioxidants. This study aimed to explore whether OBS is associated with heart failure in US adults. Methods A cross-sectional investigation was carried out using information from the National Health and Nutrition Examination Survey 2007–2018. The linear link between OBS and HF in adults aged ≥ 45 years was investigated using multivariate linear regression models. Interaction tests and subgroup analysis were also conducted. Results The prevalence of HF was 3.84%. There was a significant negative relationship between OBS (OR: 0.96 ,95%CI: 0.95–0.98, P < 0.0001) and HF. In the fully adjusted model, compared to the lowest quartile of OBS, subjects in the highest quartile had a 45% lower likelihood of developing HF (OR: 0.55, 95% CI: 0.41–0.74, p < 0.0001). In stratified analysis, OBS and HF showed no obvious negative correlation. Conclusion OBS was strongly negatively associated with heart failure. The findings underline the significance of adhering to an antioxidant diet and lifestyle, which helps prevent heart failure. |
| format | Article |
| id | doaj-art-219a1f0a652a499fbccfc266a974fed8 |
| institution | Kabale University |
| issn | 1471-2261 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
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| series | BMC Cardiovascular Disorders |
| spelling | doaj-art-219a1f0a652a499fbccfc266a974fed82025-01-26T12:14:22ZengBMCBMC Cardiovascular Disorders1471-22612025-01-012511810.1186/s12872-024-04456-zAssociations between oxidative balance scores and heart failure among americans: NHANES (2007–2018)Xiaozhuo Xu0Xueli Wang1Xu Han2Department of Geriatrics, Affiliated Hospital of Nanjing University of Chinese MedicineDepartment of Geriatrics, Affiliated Hospital of Nanjing University of Chinese MedicineDepartment of Geriatrics, Affiliated Hospital of Nanjing University of Chinese MedicineAbstract Background The relationship between oxidative balance score (OBS) and heart failure (HF) is controversial. The OBS was used to assess systemic oxidative stress status, with higher OBS scores implying exposure to more antioxidants. This study aimed to explore whether OBS is associated with heart failure in US adults. Methods A cross-sectional investigation was carried out using information from the National Health and Nutrition Examination Survey 2007–2018. The linear link between OBS and HF in adults aged ≥ 45 years was investigated using multivariate linear regression models. Interaction tests and subgroup analysis were also conducted. Results The prevalence of HF was 3.84%. There was a significant negative relationship between OBS (OR: 0.96 ,95%CI: 0.95–0.98, P < 0.0001) and HF. In the fully adjusted model, compared to the lowest quartile of OBS, subjects in the highest quartile had a 45% lower likelihood of developing HF (OR: 0.55, 95% CI: 0.41–0.74, p < 0.0001). In stratified analysis, OBS and HF showed no obvious negative correlation. Conclusion OBS was strongly negatively associated with heart failure. The findings underline the significance of adhering to an antioxidant diet and lifestyle, which helps prevent heart failure.https://doi.org/10.1186/s12872-024-04456-zOxidative balance scoreHeart failureNHANESDietaryLifestyle |
| spellingShingle | Xiaozhuo Xu Xueli Wang Xu Han Associations between oxidative balance scores and heart failure among americans: NHANES (2007–2018) BMC Cardiovascular Disorders Oxidative balance score Heart failure NHANES Dietary Lifestyle |
| title | Associations between oxidative balance scores and heart failure among americans: NHANES (2007–2018) |
| title_full | Associations between oxidative balance scores and heart failure among americans: NHANES (2007–2018) |
| title_fullStr | Associations between oxidative balance scores and heart failure among americans: NHANES (2007–2018) |
| title_full_unstemmed | Associations between oxidative balance scores and heart failure among americans: NHANES (2007–2018) |
| title_short | Associations between oxidative balance scores and heart failure among americans: NHANES (2007–2018) |
| title_sort | associations between oxidative balance scores and heart failure among americans nhanes 2007 2018 |
| topic | Oxidative balance score Heart failure NHANES Dietary Lifestyle |
| url | https://doi.org/10.1186/s12872-024-04456-z |
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