Modifying the platform-mediated avoidance task: A new protocol to study active avoidance within a social context in rats.
The platform-mediated active avoidance (PMA) task has been used to study the behavioral and neural mechanisms of a decision-based form of active avoidance. Across 10 days of PMA conditioning, rats learn to avoid a tone-signaled footshock by moving to a safe platform at the cost of forfeiting sucrose...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0321776 |
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| Summary: | The platform-mediated active avoidance (PMA) task has been used to study the behavioral and neural mechanisms of a decision-based form of active avoidance. Across 10 days of PMA conditioning, rats learn to avoid a tone-signaled footshock by moving to a safe platform at the cost of forfeiting sucrose reward. Prior studies utilizing the PMA task involved rats learning to avoid alone in a solitary context, but we have recently modified the task to include a social context to determine how social cues may influence PMA acquisition. Additionally, we report novel measures of social interaction that occur during Social Partner PMA conditioning. This protocol provides a detailed methodology for studying active avoidance within solitary and social contexts, as well as key considerations when employing the PMA task. |
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| ISSN: | 1932-6203 |